St Louis, MONCT07132307Now EnrollingIRB Ready

Obstructive Sleep Apnea Clinical Trial in St Louis, MO

Access cutting-edge obstructive sleep apnea treatment through this clinical trial at a research site in St Louis. Study-provided care at no cost to qualified participants.

Sponsored by Washington University School of Medicine

Quick Self-Assessment

See if you qualify for this St Louis location

Preparing your pre-screening questions…

Expert Care in St Louis

Access obstructive sleep apnea specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related obstructive sleep apnea treatment provided free

Apply for This St Louis Location

Check if you qualify for this obstructive sleep apnea clinical trial in St Louis, MO

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to St Louis

    Convenient for MO residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit St Louis site if eligible
  4. 4Begin participation

About This Obstructive Sleep Apnea Study in St Louis

The purpose of this study is to evaluate the effectiveness, feasibility, and safety of mandibular advancement devices (MAD) for treating severe obstructive sleep apnea (OSA) in patients who are CPAP intolerant and have failed hypoglossal nerve stimulation (HGNS).

Sponsor: Washington University School of Medicine

Who Can Participate

Inclusion Criteria

Age ≥ 18 years.
Ability to read, write, speak, and understand English.
Failure of hypoglossal nerve stimulation (HGNS) therapy, defined as intolerance to HGNS or insufficient AHI reduction based on modified Sher criteria while using HGNS.
Ability to insert and remove the mandibular advancement device (MAD) independently.
Ability to complete all study assessments and evaluations, including home sleep apnea tests (HSAT).
Ability to abstain from any other treatment for obstructive sleep apnea (OSA) during the entire study duration.
Access to an internet-connected device (phone, tablet, or laptop) with a camera.

Exclusion Criteria

Age over 70 years.
Inability to use a mandibular advancement device (MAD), defined as having fewer than 9 healthy teeth per dental arch.
Prior intolerance to MAD therapy.
Previous participation in a trial involving the use of oral appliances.
Chronic nasal obstruction.
Dependence on or frequent use of medications that alter consciousness, respiration, or alertness.
Insomnia and/or use of medications to treat insomnia.
Sleep disorders such as narcolepsy, insomnia, restless leg syndrome, or other disorders affecting sleep, and/or use of medications to treat such disorders.
Substance abuse.
Unstable psychiatric disorders.
Current use of a GLP-1 receptor agonist (e.g., Zepbound, Wegovy, Ozempic, Mounjaro) with ongoing, active weight loss at the time of enrollment, or recent dose escalation within the prior 8 weeks.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in St Louis?

Yes, this clinical trial (NCT07132307) has an active research site in St Louis, MO that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Obstructive Sleep Apnea Treatment Options in St Louis, MO

If you're searching for obstructive sleep apnea treatment options in St Louis, MO, this clinical trial (NCT07132307) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our St Louis research site is actively enrolling participants for this clinical trial. You'll receive care from experienced obstructive sleep apnea specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all obstructive sleep apnea clinical trials near you to find additional studies recruiting in your area.

More Lupus Trials in St Louis, MO

See all lupus clinical trials recruiting in St Louis — not just this study.

Browse Lupus Trials in St Louis →

Browse More Trials by Condition

Lupus TrialsUlcerative Colitis TrialsSleep Apnea TrialsPrurigo Nodularis TrialsSystemic Lupus Erythematosus TrialsAll Conditions →

Ready to Join in St Louis?

Take the first step toward participating in this groundbreaking clinical trial

Secure · Expert Care · St Louis, MO