Boston, MANCT04798469Now EnrollingIRB Ready

Opioid Use Clinical Trial in Boston, MA

Access cutting-edge opioid use treatment through this clinical trial at a research site in Boston. Study-provided care at no cost to qualified participants.

Sponsored by Brigham and Women's Hospital

Quick Self-Assessment

See if you qualify for this Boston location

Preparing your pre-screening questions…

Expert Care in Boston

Access opioid use specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related opioid use treatment provided free

Apply for This Boston Location

Check if you qualify for this opioid use clinical trial in Boston, MA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Boston

    Convenient for MA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Boston site if eligible
  4. 4Begin participation

About This Opioid Use Study in Boston

The aim of this trial is to evaluate whether testosterone replacement results in greater improvement in pain perception, pain tolerance, sexual function, fatigue, and quality of life when compared with placebo in men with chronic spinal pain treated with opioids who have opioid-induced hypogonadism (low testosterone).

Sponsor: Brigham and Women's Hospital

Who Can Participate

Inclusion Criteria

Men, age 18 years and older.
Chronic non-cancer spinal pain.
Use of opioid analgesics for at least 6 months.
Serum total testosterone (measured by mass spectrometry) \<348 ng/dL and/or free testosterone \<70 pg/mL.
Ability and willingness to provide informed consent.

Exclusion Criteria

History of prostate cancer or breast cancer.
Known history of organic hypogonadism (e.g., due to hypothalamic, pituitary or testicular disease).
Use of testosterone within the past 6 months.
Baseline hematocrit \>48%.
Prostate-specific antigen (PSA) level \>4 ng/mL in Caucasians or \>3 ng/mL in African-Americans.
Presence of prostate nodule or induration on digital rectal examination.
Uncontrolled congestive heart failure.
Myocardial infarction, acute coronary syndrome, revascularization surgery or stroke within 3 months.
Serum creatinine \>2.5 mg/dL.
Alanine aminotransferase (ALT) level 3 times above the upper limit of normal.
Diagnosis of bipolar disorder or schizophrenia.
Presence of metallic implants (pacemakers, aneurysm clips, etc.) that preclude the patient from undergoing functional magnetic resonance imaging (MRI). In subjects who are otherwise eligible and either do not qualify for MRI or are reluctant to undergo imaging, the investigators may consider enrolling such participants on a case-by-case basis.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Boston?

Yes, this clinical trial (NCT04798469) has an active research site in Boston, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Opioid Use Treatment Options in Boston, MA

If you're searching for opioid use treatment options in Boston, MA, this clinical trial (NCT04798469) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Boston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced opioid use specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all opioid use clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Boston, MA