NCT07489417 · University of Missouri-Columbia
Impact of Sleep Restriction on Blood Pressure Reactivity
What this study is about
The purpose of the research study is to examine the effects of shortened sleep on blood pressure.
View original scientific description
The purpose of the research study is to examine the effects of shortened sleep on blood pressure.
Interventions
BEHAVIORAL
Sleep Restriction
You will be asked to shorten your sleep to four hours.
Primary outcome measures
Blood Pressure
Time frame: Baseline and during the last 1-minute of stress
Blood pressure
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- Healthy adult men and women
- 18-45 years of age
- BMI \< 25 kg/m² (normal weight group) or ≥ 30 kg/m² (obesity group)
- Non-pregnant, non-breastfeeding, and non-nicotine users
- Self-reported history of normal sleep duration (7-9 hours/night) and bedtime prior to midnight
- Premenopausal
Exclusion criteria
- No acute or chronic conditions
- Taking no medications known to affect sleep, autonomic, metabolic, or cardiovascular function
- Self-reported history of irregular sleep
- Self-reported history of hepatic, renal, pulmonary, cardiovascular, or neurological disease, stroke or neurovascular disease, bleeding/clotting disorders, sleep apnea or other sleep disorders, diabetes, history of alcoholism or substance abuse, major cardiovascular event or surgical procedure within the past three months, or hypertension
Where
- Columbia, Missouri
Related conditions & keywords
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Mar 24, 2026 · Source of record for eligibility and locations