Study of the Research Medicine CIN-103 in Adults with Irritable Bowel Syndrome with Predominant Diarrhea (IBS-D).
The goal of this clinical trial is to evaluate if the study drug, CIN-103, can help reduce the symptoms associated with irritable bowel syndrome with predominant diarrhea (IBS-D) in adult patients. Th...
Study to Explore the Therapeutic Effect of Eluxadoline in Treating Irritable Bowel Syndrome With Diarrhea in Children
The primary objectives of this study are to explore the therapeutic effect of eluxadoline in treating irritable bowel syndrome with diarrhea (IBS-D) in pediatric participants 6-17 years of age, to eva...
Efficacy Study of IM Administered CssBA+dmLT Against Moderate-severe Diarrhea in Human Infection Model With ETEC Strain B7A in Healthy Adults
The study is designed to evaluate the safety, immunogenicity, and efficacy of the intramuscular administration of a CS6 based vaccine (CssBA) against ETEC co-administered with double mutant labile tox...
Top Cities for Diarrhea Clinical Trials
Diarrhea clinical trials are recruiting across 17 cities. Here are the cities with the most active studies:
About Diarrhea
Chronic diarrhea involves frequent, loose, or watery bowel movements lasting more than four weeks. It can result from infections, inflammatory conditions, or functional disorders. Treatment targets the underlying cause and may include dietary changes, anti-diarrheal medications, and probiotics.
Clinical trials are advancing new treatments for diarrhea. Currently, 3 studies are recruiting a combined 617 participants across the United States. Research is being conducted by 3 organizations including CinPhloro Pharma, LLC, AbbVie, National Institute of Allergy and Infectious Diseases (NIAID).
2026 Diarrhea Research Landscape
As of March 2026, the diarrhea clinical trial landscape includes 3 actively recruiting studies across 17 cities in the United States. These studies are collectively seeking 617 participants, with an average enrollment target of 206 per study.
Research is being led by 3 different organizations, including CinPhloro Pharma, LLC, AbbVie, National Institute of Allergy and Infectious Diseases (NIAID).
Geographically, diarrhea trials are most concentrated in Miami, Florida (4 trials); Little Rock, Arkansas (2 trials); Garden Grove, California (2 trials); Dothan, Alabama (1 trial); Huntsville, Alabama (1 trial) and 7 other cities.
Featured Diarrhea Studies
Highlighted recruiting studies for diarrhea, selected by enrollment size and research scope.
Study of the Research Medicine CIN-103 in Adults with Irritable Bowel Syndrome with Predominant Diarrhea (IBS-D).
The goal of this clinical trial is to evaluate if the study drug, CIN-103, can help reduce the symptoms associated with irritable bowel syndrome with predominant diarrhea (IBS-D) in adult patients. The main questions it aims to answer are: * To evaluate the efficacy of CIN-103 on symptoms of IBS-D when given to patients with IBS-D compared to a placebo. * To evaluate the safety and tolerability o...
Study to Explore the Therapeutic Effect of Eluxadoline in Treating Irritable Bowel Syndrome With Diarrhea in Children
The primary objectives of this study are to explore the therapeutic effect of eluxadoline in treating irritable bowel syndrome with diarrhea (IBS-D) in pediatric participants 6-17 years of age, to evaluate the pharmacokinetics of eluxadoline in pediatric participants with IBS-D, and to evaluate the safety and tolerability of eluxadoline in pediatric participants with IBS-D. Enrollment of 12-17 yea...
Efficacy Study of IM Administered CssBA+dmLT Against Moderate-severe Diarrhea in Human Infection Model With ETEC Strain B7A in Healthy Adults
The study is designed to evaluate the safety, immunogenicity, and efficacy of the intramuscular administration of a CS6 based vaccine (CssBA) against ETEC co-administered with double mutant labile toxin (dmLT) in preventing moderate-severe diarrhea (MSD) following challenge with ETEC strain B7A in healthy adults. Approximately 72 adult participants, divided into 4 cohorts of 18, will be randomized...
Frequently Asked Questions About Diarrhea Clinical Trials
Are there diarrhea clinical trials near me?
Yes, there are 3 diarrhea clinical trials currently recruiting across 17+ cities in the United States, including Miami, Florida; Little Rock, Arkansas; Garden Grove, California. Browse the studies above to find one at a location convenient for you.
How do I join a diarrhea clinical trial?
To join a diarrhea clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are diarrhea clinical trials free?
Yes, participation in diarrhea clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of diarrhea treatments are being studied?
Current diarrhea clinical trials are testing a range of approaches. These include new drugs, combination therapies, medical devices, and other interventions sponsored by 3 research organizations.
Is it safe to participate in diarrhea clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated March 2, 2026 from ClinicalTrials.gov
About This Data
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated March 2, 2026 · Data from ClinicalTrials.gov