Study of Plozasiran in Adults With Severe Hypertriglyceridemia at Risk of Acute Pancreatitis
This study will evaluate the efficacy and safety of plozasiran in approximately 140 adult participants with severe hypertriglyceridemia (SHTG) and history of at least two prior acute pancreatitis (AP)...
Safety and Tolerability of Pirfenidone in Acute Pancreatitis
The goal of the current pilot clinical trial is to evaluate the safety and tolerability of pirfenidone in patients with predicted moderately severe and severe acute pancreatitis. Pirfenidone is curren...
Evaluation of Pirfenidone as a Novel Therapeutic Strategy Against Recurrent Acute Pancreatitis.
This clinical will evaluate the safety, tolerability and early efficacy of pirenidone in patients with recurrent acute pancreatitis....
Pancreatic Enzyme Replacement Therapy for Acute Pancreatitis-Associated Exocrine Pancreatic Insufficiency
This study aims to evaluate if a 6-month course of pancrelipase (CREON) treatment improves symptoms of exocrine pancreatic insufficiency (EPI) after an attack of acute pancreatitis. Diagnosis of EPI i...
Study of CM4620 to Reduce the Severity of Pancreatitis Due to Asparaginase
This is a phase I/II clinical trial assessing the tolerability and efficacy of CM4620 in children and young adults with acute pancreatitis caused by asparaginase. The tolerability of CM4620 when given...
Pioglitazone Versus Empagliflozin for Chronic Pancreatitis/Recurrent Acute Pancreatitis Associated Diabetes Mellitus
The purpose of this study is to evaluate efficacy of pioglitazone (PIO) versus empagliflozin (EMPA) to improve glycemic control in people with Chronic Pancreatitis (CP) or Recurrent Acute Pancreatitis...
A Study to Evaluate the Safety and Efficacy of a Single Dose of RABI-767 in Participants With Acute Pancreatitis
The goal of this clinical trial is to test the safety and effectiveness of a single dose of RABI-767 given by endoscopic ultrasound (EUS) guided peripancreatic injection in participants with predicted...
Top Cities for Pancreatitis Clinical Trials
Pancreatitis clinical trials are recruiting across 23 cities. Here are the cities with the most active studies:
About Pancreatitis
Pancreatitis is inflammation of the pancreas that can be acute or chronic, often caused by gallstones or heavy alcohol use. Chronic pancreatitis leads to progressive damage and impaired function. Treatment includes pain management, enzyme replacement, dietary changes, and treating underlying causes.
Clinical trials are advancing new treatments for pancreatitis. Currently, 7 studies are recruiting a combined 438 participants across the United States. Research is being conducted by 6 organizations including Arrowhead Pharmaceuticals, University of Alabama at Birmingham, Ohio State University and 3 others.
2026 Pancreatitis Research Landscape
As of March 2026, the pancreatitis clinical trial landscape includes 7 actively recruiting studies across 23 cities in the United States. These studies are collectively seeking 438 participants, with an average enrollment target of 63 per study.
Research is being led by 6 different organizations, including Arrowhead Pharmaceuticals, University of Alabama at Birmingham, Ohio State University, St. Jude Children's Research Hospital, Mayo Clinic, and 1 others.
Geographically, pancreatitis trials are most concentrated in Rochester, Minnesota (3 trials); Birmingham, Alabama (2 trials); Los Angeles, California (2 trials); Chicago, Illinois (2 trials); New York, New York (2 trials) and 7 other cities.
Featured Pancreatitis Studies
Highlighted recruiting studies for pancreatitis, selected by enrollment size and research scope.
Study of Plozasiran in Adults With Severe Hypertriglyceridemia at Risk of Acute Pancreatitis
This study will evaluate the efficacy and safety of plozasiran in approximately 140 adult participants with severe hypertriglyceridemia (SHTG) and history of at least two prior acute pancreatitis (AP) events not attributed to other etiologies, with at least one occurring within the last 12 months prior to screening. Eligible participants will be randomly assigned in a double-blind manner to either...
Safety and Tolerability of Pirfenidone in Acute Pancreatitis
The goal of the current pilot clinical trial is to evaluate the safety and tolerability of pirfenidone in patients with predicted moderately severe and severe acute pancreatitis. Pirfenidone is currently approved by FDA for the treatment of idiopathic pulmonary fibrosis. Now, over 5 years of data has accumulated demonstrating safety of its use in humans. The investigators' preclinical data suggest...
Evaluation of Pirfenidone as a Novel Therapeutic Strategy Against Recurrent Acute Pancreatitis.
This clinical will evaluate the safety, tolerability and early efficacy of pirenidone in patients with recurrent acute pancreatitis.
Frequently Asked Questions About Pancreatitis Clinical Trials
Are there pancreatitis clinical trials near me?
Yes, there are 7 pancreatitis clinical trials currently recruiting across 23+ cities in the United States, including Rochester, Minnesota; Birmingham, Alabama; Los Angeles, California. Browse the studies above to find one at a location convenient for you.
How do I join a pancreatitis clinical trial?
To join a pancreatitis clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are pancreatitis clinical trials free?
Yes, participation in pancreatitis clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of pancreatitis treatments are being studied?
Current pancreatitis clinical trials are testing a range of approaches. These include new drugs, combination therapies, medical devices, and other interventions sponsored by 6 research organizations.
Is it safe to participate in pancreatitis clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated March 2, 2026 from ClinicalTrials.gov
About This Data
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated March 2, 2026 · Data from ClinicalTrials.gov