Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Short Bowel Syndrome Clinical Trials
Short Bowel Syndrome clinical trials are recruiting across 39 cities. Here are the cities with the most active studies:
Short Bowel Syndrome Trial Phases
10 research organizations are sponsoring short bowel syndrome trials.
About Short Bowel Syndrome
Short bowel syndrome is a condition where the body cannot absorb enough nutrients because a large portion of the small intestine is missing or damaged. It often results from surgical removal. Treatment includes specialized nutrition, medications, and sometimes intestinal transplantation.
Clinical trials are advancing new treatments for short bowel syndrome. Currently, 11 studies are recruiting a combined 1,663 participants across the United States. Research is being conducted by 10 organizations including Boston Children's Hospital, Takeoff41, Inc., Protara Therapeutics and 7 others.
2026 Short Bowel Syndrome Research Landscape
As of October 2026, the short bowel syndrome clinical trial landscape includes 11 actively recruiting studies across 39 cities in the United States. These studies are collectively seeking 1,663 participants, with an average enrollment target of 151 per study.
The research spans multiple phases of development: 5 studies are in NA, 3 studies are in PHASE2, 3 studies are in PHASE3. The presence of Phase 3 trials indicates that some short bowel syndrome treatments are in late-stage testing and may be approaching regulatory review.
Research is being led by 10 different organizations, including Boston Children's Hospital, Takeoff41, Inc., Protara Therapeutics, VectivBio AG, SterileCare Inc., and 5 others.
Geographically, short bowel syndrome trials are most concentrated in Boston, Massachusetts (6 trials); Chicago, Illinois (4 trials); Durham, North Carolina (4 trials); New York, New York (4 trials); Omaha, Nebraska (3 trials) and 7 other cities.
Featured Short Bowel Syndrome Studies
Highlighted recruiting studies for short bowel syndrome, selected by enrollment size and research scope.
Prospective Multisite Study of Quality of Life in Pediatric Intestinal Failure
This study proposes to quantify and describe the quality of life of children with intestinal failure, and to identify the medical and socio-economic factors that impact this quality of life, using data from multiple multidisciplinary intestinal failure centers across the United States and Canada specializing in the care of these participants.
AI-driven Total Parenteral Nutrition Platform
This study tests whether an artificial intelligence (AI) tool can help doctors order total parenteral nutrition (TPN) for babies in the neonatal intensive care unit (NICU). Premature babies often cannot eat by mouth and need nutrition delivered through an IV. Ordering TPN is complex, time-consuming, and mistakes can happen. This study will test an AI tool that suggests TPN formulas to doctors base...
Study of Choline Chloride for Injection in Adolescent and Adult Patients With Intestinal Failure Receiving Long Term Parenteral Support
TARA-001-301 is a Phase 2b/3 randomized Open-Label Dose-Selection study with an Open-Label Extension and randomized Double-Blind, Placebo-Controlled Study with Open-Label Extension to investigate the safety and efficacy of Choline Chloride for Injection (Low Dose and High Dose) versus Placebo in adolescents (ages 12 to \< 18 years of age) and adults (≥ 18 years of age) with intestinal failure rece...
Frequently Asked Questions About Short Bowel Syndrome Clinical Trials
Are there short bowel syndrome clinical trials near me?
Yes, there are 11 short bowel syndrome clinical trials currently recruiting across 39+ cities in the United States, including Boston, Massachusetts; Chicago, Illinois; Durham, North Carolina. Browse the studies above to find one at a location convenient for you.
How do I join a short bowel syndrome clinical trial?
To join a short bowel syndrome clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are short bowel syndrome clinical trials free?
Yes, participation in short bowel syndrome clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of short bowel syndrome treatments are being studied?
Current short bowel syndrome clinical trials are testing a range of approaches across NA (5 studies), PHASE2 (3 studies), PHASE3 (3 studies). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 10 research organizations.
Is it safe to participate in short bowel syndrome clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated October 15, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated October 15, 2026 · Data from ClinicalTrials.gov