Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for GERD Clinical Trials
GERD clinical trials are recruiting across 16 cities. Here are the cities with the most active studies:
GERD Trial Phases
13 research organizations are sponsoring gerd trials.
About GERD
Gastroesophageal reflux disease (GERD) is a chronic digestive disease in which stomach acid flows back into the esophagus, causing heartburn and irritation. It affects about 20% of the Western population. Treatment includes lifestyle modifications, proton pump inhibitors, and in severe cases, surgery.
Clinical trials are advancing new treatments for gerd. Currently, 16 studies are recruiting a combined 3,619 participants across the United States. Research is being conducted by 13 organizations including Case Comprehensive Cancer Center, University of Colorado, Denver, Phathom Pharmaceuticals, Inc. and 10 others.
2026 GERD Research Landscape
As of October 2026, the gerd clinical trial landscape includes 16 actively recruiting studies across 16 cities in the United States. These studies are collectively seeking 3,619 participants, with an average enrollment target of 226 per study.
The research spans multiple phases of development: 12 studies are in NA, 1 study is in PHASE3. The presence of Phase 3 trials indicates that some gerd treatments are in late-stage testing and may be approaching regulatory review.
Research is being led by 13 different organizations, including Case Comprehensive Cancer Center, University of Colorado, Denver, Phathom Pharmaceuticals, Inc., Nationwide Children's Hospital, Medical College of Wisconsin, and 8 others. The large number of sponsors reflects significant research interest and investment in gerd treatment advancement.
Geographically, gerd trials are most concentrated in Milwaukee, Wisconsin (3 trials); Aurora, Colorado (2 trials); Chicago, Illinois (2 trials); Kansas City, Missouri (2 trials); Baltimore, Maryland (1 trial) and 7 other cities.
Featured GERD Studies
Highlighted recruiting studies for gerd, selected by enrollment size and research scope.
Multi-Site Detection of Barrett's Esophagus in Patients Without Chronic GERD Symptoms
The goal of this clinical trial is to develop a method to detect Barrett's esophagus in individuals with a new office based diagnostic test. Barrett's esophagus is a condition in which the flat pink lining of the swallowing tube that connects the mouth to the stomach (the esophagus) becomes damaged by acid reflux. The main question it aims to answer is: Can this approach demonstrate efficacy for s...
Patient Preferences for Barrett's Esophagus and Esophageal Cancer Screening Tests
This study plans to learn more about what patients think about screening for esophageal cancer (EAC) and Barrett's esophagus (BE); a pre-cancerous condition associated with esophageal cancer. The plan is to use this information to modify screening practices in the United States with the goal to decrease the number of people who die from esophageal cancer.
A Study to Evaluate the Efficacy and Safety of Vonoprazan 10 mg Compared to Placebo for Relief of Episodic Heartburn in Participants With Symptomatic Non-Erosive Gastroesophageal Reflux Disease Through 24 Weeks
The main objective is to assess the efficacy of vonoprazan (10 mg as needed) compared to placebo (as needed) in relief of episodic heartburn at 2 hours that is sustained for 24 hours over 12 weeks of treatment in participants with non-erosive gastroesophageal reflux disease (GERD).
Frequently Asked Questions About GERD Clinical Trials
Are there gerd clinical trials near me?
Yes, there are 16 gerd clinical trials currently recruiting across 16+ cities in the United States, including Milwaukee, Wisconsin; Aurora, Colorado; Chicago, Illinois. Browse the studies above to find one at a location convenient for you.
How do I join a gerd clinical trial?
To join a gerd clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are gerd clinical trials free?
Yes, participation in gerd clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of gerd treatments are being studied?
Current gerd clinical trials are testing a range of approaches across NA (12 studies), PHASE3 (1 study). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 13 research organizations.
Is it safe to participate in gerd clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated October 19, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated October 19, 2026 · Data from ClinicalTrials.gov