Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Narcolepsy Type 1 Clinical Trials
Narcolepsy Type 1 clinical trials are recruiting across 32 cities. Here are the cities with the most active studies:
Narcolepsy Type 1 Trial Phases
5 research organizations are sponsoring narcolepsy type 1 trials.
About Narcolepsy Type 1
Narcolepsy type 1 is characterized by excessive daytime sleepiness and sudden loss of muscle tone (cataplexy), caused by loss of hypocretin-producing neurons in the brain. It affects about 1 in 2,000 people. Treatment includes stimulants, sodium oxybate, and newer orexin receptor agonists.
Clinical trials are advancing new treatments for narcolepsy type 1. Currently, 8 studies are recruiting a combined 946 participants across the United States. Research is being conducted by 5 organizations including Centessa Pharmaceuticals (UK) Limited, Alkermes, Inc., Vertex Pharmaceuticals Incorporated and 2 others.
2026 Narcolepsy Type 1 Research Landscape
As of July 2026, the narcolepsy type 1 clinical trial landscape includes 8 actively recruiting studies across 32 cities in the United States. These studies are collectively seeking 946 participants, with an average enrollment target of 118 per study.
The research spans multiple phases of development: 4 studies are in PHASE2, 4 studies are in PHASE3, 1 study is in PHASE1. The presence of Phase 3 trials indicates that some narcolepsy type 1 treatments are in late-stage testing and may be approaching regulatory review.
Research is being led by 5 different organizations, including Centessa Pharmaceuticals (UK) Limited, Alkermes, Inc., Vertex Pharmaceuticals Incorporated, Takeda, Stanford University.
Geographically, narcolepsy type 1 trials are most concentrated in Miami, Florida (6 trials); Cincinnati, Ohio (4 trials); Winter Park, Florida (3 trials); Redwood City, California (3 trials); Denver, North Carolina (2 trials) and 7 other cities.
Featured Narcolepsy Type 1 Studies
Highlighted recruiting studies for narcolepsy type 1, selected by enrollment size and research scope.
A Study to Investigate the Effects of Cleminorexton Compared With Placebo in the Treatment of Participants With Central Disorders of Hypersomnolence
Narcolepsy Type 1 (NT1) and Narcolepsy Type 2 (NT2) are rare conditions that make people feel very sleepy during the day (often referred to as excessive daytime sleepiness \[EDS\]). People living with these conditions might find it hard to stay alert and pay attention when they are at school, working, driving, or performing other daily activities. While all conditions result in feeling sleepy, th...
A Study to Evaluate the Efficacy, Safety and Tolerability of ALKS 2680 in Adults With Narcolepsy Type 1 (Brilliance NT1 - 304)
The purpose of this study is to measure decreases in daytime sleepiness, cataplexy (sudden loss of muscle tone), and disease symptoms in participants with NT1 when taking ALKS 2680 tablets compared with placebo tablets.
A Study to Evaluate the Efficacy and Safety of ALKS 2680 in Adults With Narcolepsy Type 1
The purpose of this study is to measure decreases in daytime sleepiness, cataplexy (sudden loss of muscle tone), and disease symptoms in participants with NT1 when taking ALKS 2680 tablets compared with placebo tablets.
Frequently Asked Questions About Narcolepsy Type 1 Clinical Trials
Are there narcolepsy type 1 clinical trials near me?
Yes, there are 8 narcolepsy type 1 clinical trials currently recruiting across 32+ cities in the United States, including Miami, Florida; Cincinnati, Ohio; Winter Park, Florida. Browse the studies above to find one at a location convenient for you.
How do I join a narcolepsy type 1 clinical trial?
To join a narcolepsy type 1 clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are narcolepsy type 1 clinical trials free?
Yes, participation in narcolepsy type 1 clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of narcolepsy type 1 treatments are being studied?
Current narcolepsy type 1 clinical trials are testing a range of approaches across PHASE2 (4 studies), PHASE3 (4 studies), PHASE1 (1 study). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 5 research organizations.
Is it safe to participate in narcolepsy type 1 clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 14, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 14, 2026 · Data from ClinicalTrials.gov