Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Prader-Willi Syndrome Clinical Trials
Prader-Willi Syndrome clinical trials are recruiting across 14 cities. Here are the cities with the most active studies:
Prader-Willi Syndrome Trial Phases
5 research organizations are sponsoring prader-willi syndrome trials.
About Prader-Willi Syndrome
Prader-Willi syndrome is a rare genetic disorder caused by loss of gene function on chromosome 15, leading to constant hunger, obesity, intellectual disability, and short stature. It is the most common genetic cause of life-threatening obesity. Management includes growth hormone therapy and strict dietary supervision.
Clinical trials are advancing new treatments for prader-willi syndrome. Currently, 5 studies are recruiting a combined 226 participants across the United States. Research is being conducted by 5 organizations including Harmony Biosciences Management, Inc., Maimonides Medical Center, Brigham and Women's Hospital and 2 others.
2026 Prader-Willi Syndrome Research Landscape
As of July 2026, the prader-willi syndrome clinical trial landscape includes 5 actively recruiting studies across 14 cities in the United States. These studies are collectively seeking 226 participants, with an average enrollment target of 45 per study.
The research spans multiple phases of development: 3 studies are in NA, 1 study is in PHASE3, 1 study is in PHASE2. The presence of Phase 3 trials indicates that some prader-willi syndrome treatments are in late-stage testing and may be approaching regulatory review.
Research is being led by 5 different organizations, including Harmony Biosciences Management, Inc., Maimonides Medical Center, Brigham and Women's Hospital, ConSynance Therapeutics, Children's Mercy Hospital Kansas City.
Geographically, prader-willi syndrome trials are most concentrated in Los Angeles, California (1 trial); Sacramento, California (1 trial); San Diego, California (1 trial); Aurora, Colorado (1 trial); Wilmington, Delaware (1 trial) and 7 other cities.
Featured Prader-Willi Syndrome Studies
Highlighted recruiting studies for prader-willi syndrome, selected by enrollment size and research scope.
A Study of Pitolisant in Patients With Prader-Willi Syndrome
This is a Phase 3, randomized, double-blind, placebo-controlled, multicenter, global clinical study to assess the efficacy and safety of pitolisant in patients living with Prader-Willi syndrome. The primary objective of this study is to evaluate the efficacy of pitolisant in treating excessive daytime sleepiness (EDS) in patients ≥6 years of age with Prader-Willi syndrome. Secondary objectives i...
Impact of Bright Light Therapy on Prader-Willi Syndrome
This is a placebo controlled clinical trial to assess the utility of light therapy as a sufficient treatment for excessive daytime sleepiness in patients with Prader-Willi Syndrome
Cerebellar TMS and Satiety in Prader-Willi Syndrome
This study uses a noninvasive technique called transcranial magnetic stimulation (TMS) to study hyperphagia and satiety in Prader-Willi syndrome. TMS is a noninvasive way of stimulating the brain, using a magnetic field to change activity in the brain. The magnetic field is produced by a coil that is held next to the scalp. In this study, the investigators will be stimulating the brain to learn m...
Frequently Asked Questions About Prader-Willi Syndrome Clinical Trials
Are there prader-willi syndrome clinical trials near me?
Yes, there are 5 prader-willi syndrome clinical trials currently recruiting across 14+ cities in the United States, including Los Angeles, California; Sacramento, California; San Diego, California. Browse the studies above to find one at a location convenient for you.
How do I join a prader-willi syndrome clinical trial?
To join a prader-willi syndrome clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are prader-willi syndrome clinical trials free?
Yes, participation in prader-willi syndrome clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of prader-willi syndrome treatments are being studied?
Current prader-willi syndrome clinical trials are testing a range of approaches across NA (3 studies), PHASE3 (1 study), PHASE2 (1 study). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 5 research organizations.
Is it safe to participate in prader-willi syndrome clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 16, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 16, 2026 · Data from ClinicalTrials.gov