Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis
To Evaluate the Effect of Seladelpar on Clinical Outcomes in Patients with Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis....
A Long-Term Study of Elafibranor in Adult Participants With Primary Biliary Cholangitis
The participants of this study will have confirmed Primary Biliary Cholangitis (PBC) and cirrhosis (scarring of the liver). PBC is a slowly progressive disease, characterised by damage to the bile du...
A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Biliary Cholangitis
The purpose of this clinical research study is to learn more about the use of the study medicine, volixibat, for the treatment of pruritus (itching) associated with Primary Biliary Cholangitis (PBC), ...
Open-Label Extension Study of Saroglitazar Magnesium in Participants With Primary Biliary Cholangitis
Open-Label Extension Study of Saroglitazar Magnesium in Participants With Primary Biliary Cholangitis...
Top Cities for Primary Biliary Cholangitis Clinical Trials
Primary Biliary Cholangitis clinical trials are recruiting across 22 cities. Here are the cities with the most active studies:
About Primary Biliary Cholangitis
Primary biliary cholangitis (PBC) is a chronic autoimmune liver disease in which the bile ducts in the liver are slowly destroyed. This leads to bile buildup, liver damage, and potentially cirrhosis. Treatment includes ursodeoxycholic acid and obeticholic acid.
Clinical trials are advancing new treatments for primary biliary cholangitis. Currently, 4 studies are recruiting a combined 1,004 participants across the United States. Research is being conducted by 4 organizations including Gilead Sciences, Ipsen, Mirum Pharmaceuticals, Inc. and 1 others.
2026 Primary Biliary Cholangitis Research Landscape
As of March 2026, the primary biliary cholangitis clinical trial landscape includes 4 actively recruiting studies across 22 cities in the United States. These studies are collectively seeking 1,004 participants, with an average enrollment target of 251 per study.
Research is being led by 4 different organizations, including Gilead Sciences, Ipsen, Mirum Pharmaceuticals, Inc., Zydus Therapeutics Inc..
Geographically, primary biliary cholangitis trials are most concentrated in Los Angeles, California (7 trials); Sacramento, California (3 trials); Miami, Florida (3 trials); Aurora, Colorado (3 trials); Pasadena, California (2 trials) and 7 other cities.
Featured Primary Biliary Cholangitis Studies
Highlighted recruiting studies for primary biliary cholangitis, selected by enrollment size and research scope.
Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis
To Evaluate the Effect of Seladelpar on Clinical Outcomes in Patients with Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis.
A Long-Term Study of Elafibranor in Adult Participants With Primary Biliary Cholangitis
The participants of this study will have confirmed Primary Biliary Cholangitis (PBC) and cirrhosis (scarring of the liver). PBC is a slowly progressive disease, characterised by damage to the bile ducts in the liver, leading to a build-up of bile acids which causes further damage. The liver damage in PBC may lead to cirrhosis. PBC may also be associated with multiple symptoms. Many patients with...
A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Biliary Cholangitis
The purpose of this clinical research study is to learn more about the use of the study medicine, volixibat, for the treatment of pruritus (itching) associated with Primary Biliary Cholangitis (PBC), and to assess the possible impact on the disease progression of PBC.
Frequently Asked Questions About Primary Biliary Cholangitis Clinical Trials
Are there primary biliary cholangitis clinical trials near me?
Yes, there are 4 primary biliary cholangitis clinical trials currently recruiting across 22+ cities in the United States, including Los Angeles, California; Sacramento, California; Miami, Florida. Browse the studies above to find one at a location convenient for you.
How do I join a primary biliary cholangitis clinical trial?
To join a primary biliary cholangitis clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are primary biliary cholangitis clinical trials free?
Yes, participation in primary biliary cholangitis clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of primary biliary cholangitis treatments are being studied?
Current primary biliary cholangitis clinical trials are testing a range of approaches. These include new drugs, combination therapies, medical devices, and other interventions sponsored by 4 research organizations.
Is it safe to participate in primary biliary cholangitis clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated March 2, 2026 from ClinicalTrials.gov
About This Data
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated March 2, 2026 · Data from ClinicalTrials.gov