Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Trigeminal Neuralgia Clinical Trials
Trigeminal Neuralgia clinical trials are recruiting across 3 cities. Here are the cities with the most active studies:
Trigeminal Neuralgia Trial Phases
3 research organizations are sponsoring trigeminal neuralgia trials.
About Trigeminal Neuralgia
Trigeminal neuralgia is a chronic pain condition affecting the trigeminal nerve in the face, causing sudden, severe episodes of facial pain. It is one of the most painful conditions known. Treatment includes anticonvulsant medications and surgical procedures.
Clinical trials are advancing new treatments for trigeminal neuralgia. Currently, 5 studies are recruiting a combined 155 participants across the United States. Research is being conducted by 3 organizations including George Washington University, University of Minnesota, Stanford University.
2026 Trigeminal Neuralgia Research Landscape
As of July 2026, the trigeminal neuralgia clinical trial landscape includes 5 actively recruiting studies across 3 cities in the United States. These studies are collectively seeking 155 participants, with an average enrollment target of 31 per study.
The research spans multiple phases of development: 2 studies are in PHASE4, 1 study is in EARLY_PHASE1, 1 study is in PHASE2. Early-phase studies suggest new therapeutic approaches are being explored for trigeminal neuralgia.
Research is being led by 3 different organizations, including George Washington University, University of Minnesota, Stanford University.
Geographically, trigeminal neuralgia trials are most concentrated in Minneapolis, Minnesota (2 trials); Stanford, California (2 trials); Washington D.C., District of Columbia (1 trial).
Featured Trigeminal Neuralgia Studies
Highlighted recruiting studies for trigeminal neuralgia, selected by enrollment size and research scope.
Trigger Point Injections in Anterior Cervical Surgery
To achieve appropriate exposure for an anterior neck surgery (for example an Anterior Cervical Discectomy and Fusion or ACDF), patients are positioned supine with their neck extended. Due to being in this position, patients frequently complain of posterior neck stiffness and pain postoperatively in addition to the anterior incisional pain. This posterior cervical pain can be classified as myofasci...
Trigeminal Neuralgia Electrophysiology
The study intervention is to perform standard somatosensory evoked responses limited to the face during rhizotomy procedures of the gasserian ganglion (trigeminal ganglion) for the treatment of trigeminal neuralgia. The evoked responses will be measured at two locations before and after the clinical rhizotomy including: the standard contralateral scalp (EEG) and at the gasserian ganglion through a...
Trigeminal Evoked Responses to Improve Rhizotomy
Trigeminal neuralgia (TGN) is a debilitating pain syndrome where electrical, shock- like jolts of pain affect the face. Trigeminal somatosensory evoked potentials (TSEPs) provide a promising modality for measuring the trigeminal sensory and nociceptive pathway by using peripheral stimulation of the trigeminal nerve (on the skin) and measuring low latency evoked potentials on the scalp (contralater...
Frequently Asked Questions About Trigeminal Neuralgia Clinical Trials
Are there trigeminal neuralgia clinical trials near me?
Yes, there are 5 trigeminal neuralgia clinical trials currently recruiting across 3+ cities in the United States, including Minneapolis, Minnesota; Stanford, California; Washington D.C., District of Columbia. Browse the studies above to find one at a location convenient for you.
How do I join a trigeminal neuralgia clinical trial?
To join a trigeminal neuralgia clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are trigeminal neuralgia clinical trials free?
Yes, participation in trigeminal neuralgia clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of trigeminal neuralgia treatments are being studied?
Current trigeminal neuralgia clinical trials are testing a range of approaches across PHASE4 (2 studies), EARLY_PHASE1 (1 study), PHASE2 (1 study). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 3 research organizations.
Is it safe to participate in trigeminal neuralgia clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 15, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 15, 2026 · Data from ClinicalTrials.gov