Study of VGA039 in Healthy Volunteers and Patients With Von Willebrand Disease (VIVID)
The VIVID study is structured in a master protocol format comprised of multiple parts that evaluate intravenous (IV) and subcutaneous (SC) VGA039 in healthy volunteers and subjects with von Willebrand...
A Study of Recombinant Von Willebrand Factor (rVWF) With or Without ADVATE in Children With Severe Von Willebrand Disease (VWD)
The main aim of the study is to check effectiveness, side effects, and tolerability of vonicog alfa (recombinant von Willebrand factor \[rVWF\]), with or without ADVATE, in the treatment and control o...
A Study of Vonicog Alfa (rVWF) in Children With Severe Von Willebrand Disease (vWD)
The main aim of the study is to evaluate the effectiveness of prophylaxis with vonicog alfa (recombinant von Willebrand factor \[rVWF\]) in children. This study will enroll those participants who have...
Top Cities for Von Willebrand Disease Clinical Trials
Von Willebrand Disease clinical trials are recruiting across 29 cities. Here are the cities with the most active studies:
About Von Willebrand Disease
Von Willebrand disease is the most common inherited bleeding disorder, caused by deficiency or dysfunction of von Willebrand factor, a protein needed for blood clotting. Most cases are mild with excessive bleeding during surgery or dental work. Treatment includes desmopressin and von Willebrand factor concentrates.
Clinical trials are advancing new treatments for von willebrand disease. Currently, 3 studies are recruiting a combined 171 participants across the United States. Research is being conducted by 3 organizations including Vega Therapeutics, Inc, Baxalta now part of Shire, Takeda.
2026 Von Willebrand Disease Research Landscape
As of March 2026, the von willebrand disease clinical trial landscape includes 3 actively recruiting studies across 29 cities in the United States. These studies are collectively seeking 171 participants, with an average enrollment target of 57 per study.
Research is being led by 3 different organizations, including Vega Therapeutics, Inc, Baxalta now part of Shire, Takeda.
Geographically, von willebrand disease trials are most concentrated in Aurora, Colorado (2 trials); Los Angeles, California (1 trial); Sacramento, California (1 trial); Atlanta, Georgia (1 trial); Morrisville, North Carolina (1 trial) and 7 other cities.
Featured Von Willebrand Disease Studies
Highlighted recruiting studies for von willebrand disease, selected by enrollment size and research scope.
Study of VGA039 in Healthy Volunteers and Patients With Von Willebrand Disease (VIVID)
The VIVID study is structured in a master protocol format comprised of multiple parts that evaluate intravenous (IV) and subcutaneous (SC) VGA039 in healthy volunteers and subjects with von Willebrand Disease (VWD) and other bleeding disorders.
A Study of Recombinant Von Willebrand Factor (rVWF) With or Without ADVATE in Children With Severe Von Willebrand Disease (VWD)
The main aim of the study is to check effectiveness, side effects, and tolerability of vonicog alfa (recombinant von Willebrand factor \[rVWF\]), with or without ADVATE, in the treatment and control of nonsurgical bleeding events in pediatric participants (less than (\<)18 years of age) with severe hereditary von Willebrand disease (VWD). The participants will be treated with vonicog alfa for 12-...
A Study of Vonicog Alfa (rVWF) in Children With Severe Von Willebrand Disease (vWD)
The main aim of the study is to evaluate the effectiveness of prophylaxis with vonicog alfa (recombinant von Willebrand factor \[rVWF\]) in children. This study will enroll those participants who have been previously treated with VWF product or with a plasma-derived VWF (pdVWF) product. In this study, participants will be treated with vonicog alfa (rVWF) for 12 months. During the study, participa...
Frequently Asked Questions About Von Willebrand Disease Clinical Trials
Are there von willebrand disease clinical trials near me?
Yes, there are 3 von willebrand disease clinical trials currently recruiting across 29+ cities in the United States, including Aurora, Colorado; Los Angeles, California; Sacramento, California. Browse the studies above to find one at a location convenient for you.
How do I join a von willebrand disease clinical trial?
To join a von willebrand disease clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are von willebrand disease clinical trials free?
Yes, participation in von willebrand disease clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of von willebrand disease treatments are being studied?
Current von willebrand disease clinical trials are testing a range of approaches. These include new drugs, combination therapies, medical devices, and other interventions sponsored by 3 research organizations.
Is it safe to participate in von willebrand disease clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated March 2, 2026 from ClinicalTrials.gov
About This Data
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated March 2, 2026 · Data from ClinicalTrials.gov