Philadelphia, PA7 Active Studies

Lung Cancer Clinical Trials in Philadelphia, PA

Find 7 actively recruiting lung cancer clinical trials in Philadelphia, PA. Connect with local research sites and explore new treatment options.

7
Active Trials
7
Sponsors
824
Enrolling

Recruiting Lung Cancer Studies in Philadelphia

RecruitingPhiladelphia, PANCT05142696

A Study of [177Lu]Lu-DOTA-TATE in Newly Diagnosed ES-SCLC Patients in Combination With Carboplatin, Etoposide and Atezolizumab

This study aims to establish a safe and well tolerated dose of \[177Lu\]Lu-DOTA-TATE in combination with carboplatin, etoposide and atezolizumab in this setting and to assess preliminary efficacy of t...

200 participants
Novartis Pharmaceuticals
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RecruitingPhiladelphia, PANCT06043817

First-In-Human Study of STX-721 in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Harboring EGFR Exon 20 Insertion Mutations

Study STX-721-101 is an open label, Phase 1/2 study evaluating the safety, tolerability, pharmacokinetic (PK) exposure, and preliminary antitumor activity of STX-721 in participants with non-small cel...

185 participants
Antares Therapeutics, Inc
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RecruitingPhiladelphia, PANCT06667908

A Study of JNJ-90301900 in Combination With Chemoradiation Followed by Consolidation Immunotherapy for Non-Small Cell Lung Cancer (NSCLC)

The purpose of this study is to determine whether JNJ-90301900 added to concurrent platinum-based doublet chemotherapy with radiation therapy (cCRT) followed by consolidation immunotherapy (cIT) can i...

130 participants
Johnson & Johnson Enterprise Innovation Inc.
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RecruitingPhiladelphia, PANCT05456256

A Study of LP-300 With Carboplatin and Pemetrexed in Never Smokers With Advanced Lung Adenocarcinoma

The goal of this clinical trial is to determine clinical advantages for LP-300 in combination with carboplatin and pemetrexed in the never smoker patient population. The primary objectives of this stu...

90 participants
Lantern Pharma Inc.
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RecruitingPhiladelphia, PANCT06731907

A Study of Pembrolizumab With or Without Chemotherapy in Combination With Additional Treatments for Advanced Non-Small Cell Lung Cancer (NSCLC) (MK-3475-01G/KEYMAKER U01)

Researchers are investigating new treatments for untreated advanced non-small cell lung cancer (NSCLC), which is the most common form of lung cancer and lung cancer that has spread beyond surgical rem...

90 participants
Merck Sharp & Dohme LLC
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RecruitingPhiladelphia, PANCT07174583

A Study of IDE849 in Patients With DLL3 Expressing Tumors Including Small Cell Lung Cancer

This is Phase 1/2, multicenter, clinical study to evaluate the safety, efficacy, PK, and immunogenicity of IDE849 in subjects with DLL3-expressing tumors including SCLC....

90 participants
IDEAYA Biosciences
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RecruitingPhiladelphia, PANCT03527108

Nivolumab Plus Ramucirumab in Patients With Recurrent, Advanced, Metastatic NSCLC

The study will enroll patients with prior IO therapy (alone or in combination with chemotherapy or in combination with other IO agents) regardless of the PD-L1 level, into a non-randomized combination...

39 participants
Fox Chase Cancer Center
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About Lung Cancer Clinical Trials in Philadelphia

Lung cancer is the leading cause of cancer death worldwide, starting in the cells of the lungs. The two main types are non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). Treatments include surgery, chemotherapy, radiation, immunotherapy, and targeted drugs.

There are currently 7 lung cancer clinical trials recruiting participants in Philadelphia, PA. These studies are seeking a combined 824 participants. Research is being sponsored by Novartis Pharmaceuticals, Antares Therapeutics, Inc, Johnson & Johnson Enterprise Innovation Inc. and 4 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Lung Cancer Clinical Trials in Philadelphia — FAQ

Are there lung cancer clinical trials in Philadelphia?

Yes, there are 7 lung cancer clinical trials currently recruiting in Philadelphia, PA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Philadelphia?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Philadelphia research site will contact you about next steps.

Are clinical trials in Philadelphia free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Philadelphia studies also compensate for your time and travel.

What lung cancer treatments are being tested?

The 7 active trials in Philadelphia are testing new therapies including novel drugs, biologics, and treatment approaches for lung cancer.

Data updated March 2, 2026 from ClinicalTrials.gov