10 Ovarian Cancer Clinical Trials in Philadelphia, PA (2026)

Q: How do I join a clinical trial in Philadelphia?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Philadelphia research site will contact you.

Recruiting Ovarian Cancer Studies in Philadelphia

NCT04590326Recruiting

A Study to Find Out How Safe REGN5668 is and How Well it Works In Adult Women When Given With Either Cemiplimab, or Cemiplimab + Fianlimab, or Ubamatamab

This study is researching an investigational drug called REGN5668 : * alone or, * combined with cemiplimab (also known as REGN2810) or, * combined with both cemiplimab and fianlimab (also known as RE...

Philadelphia, PAPHASE1612 participantsRegeneron Pharmaceuticals

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NCT07546500Recruiting

A Study of Azenosertib (ZN-c3) Versus Investigator's Choice Chemotherapy in Subjects With Platinum-Resistant High-Grade Serous Ovarian, Primary Peritoneal, or Fallopian Tube Cancers Positive for Cyclin E1 Protein Expression

This is a randomized, Phase 3 trial designed to evaluate the efficacy and safety of azenosertib compared to Investigator's choice of chemotherapy in subjects with platinum-resistant ovarian cancer who...

Philadelphia, PAPHASE3420 participantsK-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc

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NCT01000259Recruiting

Study of Tumor Tissue Samples From Patients Who Have Undergone Surgery for Advanced Stage III or Stage IV Ovarian Epithelial Cancer

This research study is looking at tumor tissue samples from patients who have undergone surgery for advanced stage III or stage IV ovarian epithelial cancer. Studying samples of tumor tissue from pati...

Philadelphia, PA174 participantsGynecologic Oncology Group

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NCT06515613Recruiting

A Phase 1 Study of CTIM-76 in Patients With Recurring Ovarian Cancer and Other Advanced Solid Tumors

This is a Phase 1a/1b, open-label, dose escalation and expansion study to evaluate the safety and efficacy of CTIM-76 (study drug), a CLDN6-directed T cell-engaging bispecific antibody , in participan...

Philadelphia, PAPHASE1156 participantsContext Therapeutics Inc.

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NCT06774963Recruiting

A Phase 1 Study of LNCB74 in Advanced Solid Tumors

This is an open-label, phase 1, dose escalation and dose expansion study to determine safety and tolerability, and to determine the maximum tolerated dose and / or recommended phase 2 dose of LNCB74 i...

Philadelphia, PAPHASE1145 participantsNextCure, Inc.

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NCT05287451Recruiting

Risk Reducing Salpingectomy With Delayed Oophorectomy as an Alternative to Risk- Reducing Salpingo-oophorectomy in High Risk-Women to Assess the Safety of Prevention - US Cohort Study

This is a prospective preference study that will evaluate non-inferiority of the innovative treatment (RRS with delayed RRO) as compared to the standard treatment (RRSO) with respect to high grade ser...

Philadelphia, PANA100 participantsM.D. Anderson Cancer Center

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NCT06962059Recruiting

Healthy Volunteers Study

The purpose of this study is to examine the role of the bacterial environments and metabolites in the early detection and prediction of ovarian cancer development. Vaginal swabs and stool samples will...

Philadelphia, PA50 participantsAbramson Cancer Center at Penn Medicine

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NCT05568680Recruiting

SynKIR-110 for Mesothelin Expressing Ovarian Cancer, Cholangiocarcinoma or Mesothelioma

This first-in-human (FIH) trial is designed to assess the safety, feasibility, and potential activity of a single intravenous (IV) dose of SynKIR-110 administered to subjects with mesothelin-expressin...

Philadelphia, PAPHASE142 participantsVerismo Therapeutics

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NCT02637934Recruiting

Phase I Pilot Study of Biodistribution, Metabolism and Excretion of Novel Radiotracer [18F]Fluorthanatrace (FTT) by PET/CT

Up to 40 evaluable women with known or suspected epithelial ovarian, fallopian tube, or primary peritoneal cancer will participate in two different imaging cohorts. The Biodistribution cohort will inc...

Philadelphia, PAPHASE135 participantsAbramson Cancer Center at Penn Medicine

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NCT06930755Recruiting

Study of NMS-03305293 in Adult Patients With Relapsed Ovarian Cancer

This is a multicenter, open-label Phase Ia/b study on the safety and efficacy of the combination of NMS-03305293 and topotecan in patients with recurrent ovarian cancer, with dose-limiting toxicity (D...

Philadelphia, PAPHASE124 participantsNerviano Medical Sciences

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About Ovarian Cancer Clinical Trials in Philadelphia

Ovarian cancer originates in the ovaries or fallopian tubes and is often called a "silent killer" due to subtle early symptoms. It is the fifth leading cause of cancer death among women. Treatment typically involves surgery and chemotherapy, with newer targeted therapies showing promise.

There are currently 10 ovarian cancer clinical trials recruiting participants in Philadelphia, PA. These studies are seeking a combined 1,758 participants. Research is being sponsored by Regeneron Pharmaceuticals, K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc, Gynecologic Oncology Group and 6 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Ovarian Cancer Clinical Trials in Philadelphia — FAQ

Are there ovarian cancer clinical trials in Philadelphia?

Yes, there are 10 ovarian cancer clinical trials currently recruiting in Philadelphia, PA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Philadelphia?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Philadelphia research site will contact you about next steps.

Are clinical trials in Philadelphia free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Philadelphia studies also compensate for your time and travel.

What ovarian cancer treatments are being tested?

The 10 active trials in Philadelphia are testing new therapies including novel drugs, biologics, and treatment approaches for ovarian cancer.

Data updated July 17, 2026 from ClinicalTrials.gov