8 Pancreatic Cancer Clinical Trials in Philadelphia, PA (2026)

Q: How do I join a clinical trial in Philadelphia?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Philadelphia research site will contact you.

Recruiting Pancreatic Cancer Studies in Philadelphia

NCT02000089Recruiting

The Cancer of the Pancreas Screening-5 CAPS5)Study

Johns Hopkins clinical research office quality assurance group will monitor and audit this study at Johns Hopkins. The Sub Investigator at each site will be responsible for internal monitoring at thei...

Philadelphia, PAPHASE39,000 participantsJohns Hopkins University

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NCT02478892Recruiting

Preliminary Evaluation of Screening for Pancreatic Cancer in Patients With Inherited Genetic Risk

The study is a prospective, observational study evaluating the utility of endoscopic ultrasound or MRI for the identification of preneoplastic and neoplastic pancreatic lesions in patients at high ris...

Philadelphia, PA200 participantsAbramson Cancer Center at Penn Medicine

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NCT02843945Recruiting

Initial Feasibility Study to Treat Borderline Resectable Pancreatic Cancer With a Planar LDR Source

Initial study to evaluate local control and the preferred method of attachment of the CivaSheet in the setting of suspected close or positive margins at the time of surgical tumor removal....

Philadelphia, PAPHASE180 participantsCivaTech Oncology

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NCT06747845Recruiting

Maintenance Niraparib Plus Ipilimumab in Patients With Metastatic Pancreatic Adenocarcinoma Whose Disease Has Not Progressed on Platinum-Based Chemotherapy

The main goal of this study is to look at the effectiveness and anti-tumor activity (preventing growth of the tumor) of the drugs niraparib and ipilimumab, on the patients and their pancreatic cancer....

Philadelphia, PAPHASE268 participantsAbramson Cancer Center at Penn Medicine

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NCT06048484Recruiting

Combination Therapy in Patients With Localized Pancreatic Ductal Adenocarcinoma

The purpose of this study is to combine standard radiation therapy with drugs that encourages the body's immune system against cancer cells and simultaneously adding drugs which also target the pathwa...

Philadelphia, PAPHASE260 participantsGulam Manji

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NCT07450859Recruiting

A Study of Nuzefatide Pevedotin (BT5528) in Patients With Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)

This is a Phase 2 study for nuzefatide pevedotin (BT5528) in adults with a specific type of pancreatic cancer called metastatic pancreatic ductal adenocarcinoma (PDAC) that has spread and worsened aft...

Philadelphia, PAPHASE239 participantsBicycleTx Limited

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NCT06850623Recruiting

Acoustic Cluster Therapy (ACT) With Chemotherapy for the Treatment of Locally Advanced Pancreatic Cancer

The purpose of the study is to assess the efficacy and safety of Acoustic Cluster Therapy (ACT) when given in addition to chemotherapy for treatment of Locally Advanced Pancreatic Cancer....

Philadelphia, PAPHASE225 participantsEXACT Therapeutics AS

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NCT07554560Recruiting

Nutrition Intervention for Pancreatic Cancer

Patients with pancreatic cancer (pancreatic ductal adenocarcinoma (PDAC) and pancreatic neuroendocrine tumor (NET)) commonly experience fat malabsorption due to exocrine pancreatic insufficiency (EPI)...

Philadelphia, PANA18 participantsChildren's Hospital of Philadelphia

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About Pancreatic Cancer Clinical Trials in Philadelphia

Pancreatic cancer begins in the tissues of the pancreas and is often diagnosed at an advanced stage. It is one of the most challenging cancers to treat. Clinical trials are actively investigating new approaches including immunotherapy and combination regimens.

There are currently 8 pancreatic cancer clinical trials recruiting participants in Philadelphia, PA. These studies are seeking a combined 9,490 participants. Research is being sponsored by Johns Hopkins University, Abramson Cancer Center at Penn Medicine, CivaTech Oncology and 4 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Pancreatic Cancer Clinical Trials in Philadelphia — FAQ

Are there pancreatic cancer clinical trials in Philadelphia?

Yes, there are 8 pancreatic cancer clinical trials currently recruiting in Philadelphia, PA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Philadelphia?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Philadelphia research site will contact you about next steps.

Are clinical trials in Philadelphia free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Philadelphia studies also compensate for your time and travel.

What pancreatic cancer treatments are being tested?

The 8 active trials in Philadelphia are testing new therapies including novel drugs, biologics, and treatment approaches for pancreatic cancer.

Data updated July 16, 2026 from ClinicalTrials.gov