Charleston, SCNCT04263285Now EnrollingIRB Ready

Depression Clinical Trial in Charleston, SC

Access cutting-edge depression treatment through this clinical trial at a research site in Charleston. Study-provided care at no cost to qualified participants.

Sponsored by Medical University of South Carolina

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Expert Care in Charleston

Access depression specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related depression treatment provided free

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Check if you qualify for this depression clinical trial in Charleston, SC

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Charleston

    Convenient for SC residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Charleston site if eligible
  4. 4Begin participation

About This Depression Study in Charleston

Depression is more common after a spinal cord injury (SCI) than in the general population. Unfortunately, it is unknown how depression is typically treated in individuals with SCI or if commonly used treatment methods are effective. This study will investigate the safety and impact of a novel method for treating depression called repetitive transcranial magnetic stimulation (rTMS). rTMS is a type of non-invasive brain stimulation. Fourteen individuals with a cervical or thoracic level SCI and depression will complete an approved treatment plan using rTMS. Participants will be treated using rTMS five days a week for four weeks. After four weeks of treatment, the study team will review the safety of rTMS and assess changes in depressive symptoms. If the results are positive, larger studies can be designed to develop better treatment options for individuals with SCI and depression.

Sponsor: Medical University of South Carolina

Who Can Participate

Inclusion Criteria

Age 18 - 70;
At least 6 months post incomplete cervical or incomplete or complete thoracic level SCI;
Have at least partial active movement of the right thumb (abductor pollicis brevis) to allow for FDA approved rTMS dosing;
Major depressive disorder, as identified through screening tools;
No antidepressant medications or no change in doses of psychotropic medication(s) for at least 4 weeks prior to the study (6 weeks if newly initiated medication).

Exclusion Criteria

Concomitant neurologic diseases/disorders or dementia;
Cognitive impairment, as identified through a screening tool (Montreal Cognitive Assessment);
History of major head trauma as identified through a screening tool (Ohio State University Traumatic Brain Injury Identification Method);
History of psychosis or other Axis I disorder that is primary;
Positive screen for bipolar disorder, as identified through a screening tool (The Mood Disorder Questionnaire);
Life expectancy \<1 year;
Attempt of suicide in the last 2 years;
Electronic or metallic implants (i.e. metal in the head, cochlear implant, or pacemaker);
History of seizures or currently prescribed anti-seizure medications;
Taking medication that increases the risk of seizures;
Pregnancy as identified through a positive pregnancy test;
Inability or unwillingness of subject or legal guardian/representative to give informed consent.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Charleston?

Yes, this clinical trial (NCT04263285) has an active research site in Charleston, SC that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Depression Treatment Options in Charleston, SC

If you're searching for depression treatment options in Charleston, SC, this clinical trial (NCT04263285) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Charleston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced depression specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all depression clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Charleston, SC