San Francisco, CANCT06898788Now EnrollingIRB Ready

Depression Clinical Trial in San Francisco, CA

Access cutting-edge depression treatment through this early phase 1 clinical trial at a research site in San Francisco. Study-provided care at no cost to qualified participants.

Sponsored by University of California, San Francisco

Quick Self-Assessment

See if you qualify for this San Francisco location

Preparing your pre-screening questions…

Expert Care in San Francisco

Access depression specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related depression treatment provided free

Apply for This San Francisco Location

Check if you qualify for this depression clinical trial in San Francisco, CA

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to San Francisco

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit San Francisco site if eligible
  4. 4Begin participation

About This Depression Study in San Francisco

This double-blind, placebo-controlled clinical trial will examine the effect of probiotic Visbiome on the brain and gut microbiome of individuals 15 to 24 years of age.

Sponsor: University of California, San Francisco

Who Can Participate

Inclusion Criteria

Female and male participants 15 to 24 years of age
Fluency in English
Access to smartphone, tablet, or computer, on which program "Zoom" can be run for remote visits
Diagnosed with a primary DSM-5 clinical depressive disorder (Major Depressive Disorder, Persistent Depressive Disorder, or Other Specified Depressive Disorder). The DSM-5 clinical depressive disorder will be confirmed by the Schedule for Affective Disorders and Schizophrenia for School-Aged Children-Computerized Version (K-SADS-COMP)47 to participants \<18 years and the Structured Clinic Interview for DSM-5 (SCID-V) to participants ≥18 years.
Participants must be under the care of a primary care clinician and/or mental health professional
Currently on SSRI for at least 8 weeks
BDI-II score greater than 13

Exclusion Criteria

Current diagnosis of other DSM-5 mental health disorders except for anxiety disorders and ADHD as long as depressive disorder is the primary diagnosis
Current medically-treated with stimulant medication for ADHD unless subject is on stable dosage of stimulant medication and there are no plans to change the stimulant medication or dosage for at least 8 weeks.
Current diagnosis of any Axis II personality disorder(s) as assessed by the K-SADS-COMP or SCID-V.
Oral probiotic use 1 month prior to phone screening
Oral or IV antibiotic use 1 month prior to phone screening
Fermented foods (e.g., yogurt, kombucha) 1 month prior to phone screening
Oral antioxidant or omega 3 supplements \<6 weeks prior to phone screening
Current alcohol intake greater than 2 drinks per week
Smoking cigarettes (\>5 during last 6 months) or tobacco (pipe or hookah #1 time during last month)
Any plans to make significant change in diet and lifestyle
Immunocompromised patients
Allergies to milk, soy, or yeast
Tanner Stage \<3
Current active suicidal ideation that requires psychiatric hospitalization or suicidal ideation with plan or intent to attempt suicide as assessed by the Columbia-Suicide Severity Rating Scale (C-SSRS)
Prior suicide attempt within past 6 months that required hospitalization and/or visit to the Emergency Department
History of failure to clinically respond to 2 or more adequate trials of 2 different first-line SSRI antidepressant medications
Any contraindication to MRI (e.g., braces)
Pregnancy or any plans to become pregnant during the study is an exclusion criterion for entrance into the study. Women of reproductive capability will be asked about pregnancy or plans to become pregnant. Women of reproductive capability will be asked to employ at least one of the following allowable contraception methods until they complete their second MRI: birth control implant, birth control shot, birth control patch, birth control pill, condom, internal condom, birth control sponge, cervical cap, spermicide, fertility awareness (calendar method), outercourse and abstinence.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in San Francisco?

Yes, this clinical trial (NCT06898788) has an active research site in San Francisco, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Depression Treatment Options in San Francisco, CA

If you're searching for depression treatment options in San Francisco, CA, this clinical trial (NCT06898788) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our San Francisco research site is actively enrolling participants for this early phase 1 clinical trial. You'll receive care from experienced depression specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all depression clinical trials near you to find additional studies recruiting in your area.

More Depression Trials in San Francisco, CA

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Secure · Expert Care · San Francisco, CA