Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Clostridioides Difficile Infection Clinical Trials
Clostridioides Difficile Infection clinical trials are recruiting across 40 cities. Here are the cities with the most active studies:
Clostridioides Difficile Infection Trial Phases
12 research organizations are sponsoring clostridioides difficile infection trials.
About Clostridioides Difficile Infection
Clostridioides difficile infection is a bacterial infection that causes inflammation of the colon, often following antibiotic use. It can cause severe diarrhea and life-threatening colitis. Treatment includes specific antibiotics, and fecal microbiota transplantation for recurrent cases.
Clinical trials are advancing new treatments for clostridioides difficile infection. Currently, 13 studies are recruiting a combined 3,030 participants across the United States. Research is being conducted by 12 organizations including Vedanta Biosciences, Inc., Krunal Patel, Lumen Bioscience, Inc. and 9 others.
2026 Clostridioides Difficile Infection Research Landscape
As of July 2026, the clostridioides difficile infection clinical trial landscape includes 13 actively recruiting studies across 40 cities in the United States. These studies are collectively seeking 3,030 participants, with an average enrollment target of 233 per study.
The research spans multiple phases of development: 5 studies are in PHASE2, 4 studies are in NA, 3 studies are in PHASE3, 2 studies are in PHASE1. The presence of Phase 3 trials indicates that some clostridioides difficile infection treatments are in late-stage testing and may be approaching regulatory review.
Research is being led by 12 different organizations, including Vedanta Biosciences, Inc., Krunal Patel, Lumen Bioscience, Inc., Brigham and Women's Hospital, University of Virginia, and 7 others. The large number of sponsors reflects significant research interest and investment in clostridioides difficile infection treatment advancement.
Geographically, clostridioides difficile infection trials are most concentrated in Minneapolis, Minnesota (3 trials); Phoenix, Arizona (2 trials); Hamden, Connecticut (2 trials); Huntsville, Alabama (1 trial); Chandler, Arizona (1 trial) and 7 other cities.
Featured Clostridioides Difficile Infection Studies
Highlighted recruiting studies for clostridioides difficile infection, selected by enrollment size and research scope.
VE303 for Prevention of Recurrent Clostridioides Difficile Infection
The overall objective of the RESTORATiVE303 study is to evaluate the safety and the Clostridioides difficile infection (CDI) recurrence rate at Week 8 in participants who receive a 14-day course of VE303 or matching placebo. The objectives and endpoints are identical for Stage 1 (recurrent CDI) and Stage 2 (high-risk primary CDI).
Outcomes and Data Collection for Fecal Microbiota Transplantation for the Treatment of Recurrent Clostridium Difficile
The purpose of this study is to see if stool transplant performed by colonoscopy is effective at treating recurrent Clostridium difficile (C. diff) infection of the colon. During the procedure a stool sample is taken from a healthy donor (usually family member or close friend) and transplanted directly into the colon of the patient with C. diff infection. The goal of this experimental procedure (c...
LMN-201 for Prevention of C. Difficile Infection Recurrence
This is a multisite study to evaluate the safety, tolerability, and efficacy of LMN-201 in participants recently diagnosed with CDI who are scheduled to receive or are receiving SOC antibiotic therapy against C. difficile.
Frequently Asked Questions About Clostridioides Difficile Infection Clinical Trials
Are there clostridioides difficile infection clinical trials near me?
Yes, there are 13 clostridioides difficile infection clinical trials currently recruiting across 40+ cities in the United States, including Minneapolis, Minnesota; Phoenix, Arizona; Hamden, Connecticut. Browse the studies above to find one at a location convenient for you.
How do I join a clostridioides difficile infection clinical trial?
To join a clostridioides difficile infection clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are clostridioides difficile infection clinical trials free?
Yes, participation in clostridioides difficile infection clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of clostridioides difficile infection treatments are being studied?
Current clostridioides difficile infection clinical trials are testing a range of approaches across PHASE2 (5 studies), NA (4 studies), PHASE3 (3 studies), PHASE1 (2 studies). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 12 research organizations.
Is it safe to participate in clostridioides difficile infection clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 16, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 16, 2026 · Data from ClinicalTrials.gov