Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Long COVID Clinical Trials
Long COVID clinical trials are recruiting across 33 cities. Here are the cities with the most active studies:
Long COVID Trial Phases
30 research organizations are sponsoring long covid trials.
About Long COVID
Long COVID (post-acute sequelae of SARS-CoV-2) refers to symptoms persisting weeks to months after the initial COVID-19 infection. Symptoms can include fatigue, brain fog, breathlessness, and joint pain. Research is actively investigating causes and treatments for this complex condition.
Clinical trials are advancing new treatments for long covid. Currently, 38 studies are recruiting a combined 114,914 participants across the United States. Research is being conducted by 30 organizations including Scripps Translational Science Institute, Brain Inflammation Collaborative, Wes Ely and 27 others.
2026 Long COVID Research Landscape
As of July 2026, the long covid clinical trial landscape includes 38 actively recruiting studies across 33 cities in the United States. These studies are collectively seeking 114,914 participants, with an average enrollment target of 3,024 per study.
The research spans multiple phases of development: 20 studies are in NA, 8 studies are in PHASE2, 4 studies are in PHASE3, 2 studies are in PHASE1, 1 study is in EARLY_PHASE1. The presence of Phase 3 trials indicates that some long covid treatments are in late-stage testing and may be approaching regulatory review.
Research is being led by 30 different organizations, including Scripps Translational Science Institute, Brain Inflammation Collaborative, Wes Ely, University of Chicago, Columbia University, and 25 others. The large number of sponsors reflects significant research interest and investment in long covid treatment advancement.
Geographically, long covid trials are most concentrated in New York, New York (5 trials); San Francisco, California (4 trials); Boston, Massachusetts (4 trials); Nashville, Tennessee (3 trials); Aurora, Colorado (2 trials) and 7 other cities.
Featured Long COVID Studies
Highlighted recruiting studies for long covid, selected by enrollment size and research scope.
The Long COVID-19 Wearable Device Study
To further characterize Long COVID-19 by collecting data from individuals who already own wearable devices or are provided with a wearable device along with basic and enhanced educational materials to determine if both can improve Long COVID-19 symptom management and post-exertional malaise.
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
The unhide® Project is a non-interventional, longitudinal research study designed to establish a secure data repository of demographic, health, and lifestyle information from individuals with brain inflammation and related neuroinflammatory conditions. Participants in the United States aged 2 years and older will provide self-reported health data, biometrics, and symptom diaries through the MyData...
Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary Symptoms of Long COVID
The overarching goal of this study is to determine if baricitinib, as compared to placebo, will improve neurocognitive function, along with measures of physical function, quality of life, post-exertional malaise, effect of breathlessness on daily activities, post-COVID-19 symptom burden, and biomarkers of inflammation and viral measures, in participants with Long COVID.
Frequently Asked Questions About Long COVID Clinical Trials
Are there long covid clinical trials near me?
Yes, there are 38 long covid clinical trials currently recruiting across 33+ cities in the United States, including New York, New York; San Francisco, California; Boston, Massachusetts. Browse the studies above to find one at a location convenient for you.
How do I join a long covid clinical trial?
To join a long covid clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are long covid clinical trials free?
Yes, participation in long covid clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of long covid treatments are being studied?
Current long covid clinical trials are testing a range of approaches across NA (20 studies), PHASE2 (8 studies), PHASE3 (4 studies), PHASE1 (2 studies), EARLY_PHASE1 (1 study). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 30 research organizations.
Is it safe to participate in long covid clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 14, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 14, 2026 · Data from ClinicalTrials.gov