Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Malaria Clinical Trials
Malaria clinical trials are recruiting across 3 cities. Here are the cities with the most active studies:
About Malaria
Malaria is a life-threatening parasitic disease transmitted by infected mosquitoes, primarily caused by Plasmodium falciparum. It kills hundreds of thousands of people annually, mostly in tropical regions. Prevention and treatment include antimalarial drugs, insecticide-treated nets, and ongoing vaccine research.
Clinical trials are advancing new treatments for malaria. Currently, 5 studies are recruiting a combined 2,764 participants across the United States. Research is being conducted by 3 organizations including National Institute of Allergy and Infectious Diseases (NIAID), Johns Hopkins Bloomberg School of Public Health, Eisai Inc..
2026 Malaria Research Landscape
As of July 2026, the malaria clinical trial landscape includes 5 actively recruiting studies across 3 cities in the United States. These studies are collectively seeking 2,764 participants, with an average enrollment target of 553 per study.
Research is being led by 3 different organizations, including National Institute of Allergy and Infectious Diseases (NIAID), Johns Hopkins Bloomberg School of Public Health, Eisai Inc..
Geographically, malaria trials are most concentrated in Bethesda, Maryland (3 trials); Baltimore, Maryland (1 trial); Austin, Texas (1 trial).
Featured Malaria Studies
Highlighted recruiting studies for malaria, selected by enrollment size and research scope.
Screening of Healthy Volunteers for Investigational Antimalarial Drugs, Malaria Vaccines, and Controlled Human Malaria Challenge
Background: Malaria is a serious infection caused by a parasite. People get malaria when an infected mosquito bites them. Malaria can cause major health and social problems in places were malaria is common, such as Africa but can also affect travelers who have never been exposed to malaria. Researchers at the NIH want to find a safe and effective malaria vaccine, antimalarial drugs, or prevention...
Evaluation, Treatment and Monitoring of Patients With a Known or Suspected Parasitic Infection
The purpose of this study is to evaluate, treat and follow patients with parasitic infections. People with a known or suspected parasitic infection who are at least 1 year old may be enrolled. This study does not involve any experimental treatments. Participants will have a physical examination and laboratory tests on blood, stool, or urine. Blood samples may be collected at regular intervals, b...
Induced Blood-Stage Malaria in Healthy Malaria-Naive Adults to Assess the Safety and Infectivity of Plasmodium Vivax Challenge Agent and Evaluate Transmission in Mosquito Feeding Assays
Background: Malaria is a disease caused by parasites transmitted to people by mosquitoes. Around the world, there were 241 million cases and 627,000 deaths from malaria in 2020. Researchers are working to develop vaccines and treatments for this disease. Objective: To learn how malaria develops in people; how the body's immune system reacts to malaria; and how malaria spreads from people to mos...
Frequently Asked Questions About Malaria Clinical Trials
Are there malaria clinical trials near me?
Yes, there are 5 malaria clinical trials currently recruiting across 3+ cities in the United States, including Bethesda, Maryland; Baltimore, Maryland; Austin, Texas. Browse the studies above to find one at a location convenient for you.
How do I join a malaria clinical trial?
To join a malaria clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are malaria clinical trials free?
Yes, participation in malaria clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of malaria treatments are being studied?
Current malaria clinical trials are testing a range of approaches. These include new drugs, combination therapies, medical devices, and other interventions sponsored by 3 research organizations.
Is it safe to participate in malaria clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 13, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 13, 2026 · Data from ClinicalTrials.gov