22 Lupus Clinical Trials in Boston, NY (2026)

Q: How do I join a clinical trial in Boston?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you.

Recruiting Lupus Studies in Boston

NCT05934149Recruiting

Lupus Landmark Study: A Prospective Registry and Biorepository

The purpose of the registry and biorepository is to provide a mechanism to store clinical data, linked biospecimens and molecular data to support the conduct of future research on Systemic Lupus Eryth...

Boston, NY3,500 participantsLupus Research Alliance

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NCT06621511Recruiting

OurSleepKit To Support CPAP Adherence

The goal of this clinical trial is to learn if a couple-focused mobile health intervention will improve the use of continuous positive airway pressure (CPAP), the primary treatment option for obstruct...

Boston, NY360 participantsNational Heart, Lung, and Blood Institute (NHLBI)

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NCT05869955Recruiting

A Study of CC-97540, CD-19-Targeted Nex-T CAR T Cells, in Participants With Severe, Refractory Autoimmune Diseases (Breakfree-1)

The purpose of this study is to establish the tolerability, preliminary efficacy, and pharmacokinetics of CC-97540 in participants with severe, refractory autoimmune diseases (Breakfree-1)....

Boston, NY270 participantsJuno Therapeutics, Inc., a Bristol-Myers Squibb Company

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NCT06570798Recruiting

A Phase 2a Master Protocol Assessing Inebilizumab and Blinatumomab in Autoimmune Diseases

The main objective is to assess the safety and tolerability of inebilizumab in adult participants with active and refractory systemic lupus erythematosus (SLE) with nephritis (Subprotocol A) and to as...

Boston, NY220 participantsAmgen

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NCT06581198Recruiting

A Study of Rapcabtagene Autoleucel in Systemic Lupus Erythematosus (SLE) Patients With Active, Refractory Lupus Nephritis (LN)

The purpose of this study is to evaluate the efficacy and safety of rapcabtagene autoleucel (administered once following lymphodepletion) versus Standard of Care (SOC) in patients with systemic lupus ...

Boston, NY179 participantsNovartis Pharmaceuticals

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NCT07243574Recruiting

Night Owl Sleep Study: The Effect of Sleep on Fecal Microbiota

The goal of this clinical trial is to assess differences in the fecal microbiota and metabolome associated with insufficient and sufficient sleep, and to evaluate the response and recovery of the micr...

Boston, NY174 participantsDanisco

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NCT06897930Recruiting

A Study to Investigate the Safety, Tolerability, and Efficacy of AZD0120 in Adults With Refractory SLE

This is a Phase 1b/2, single-arm, open-label, multi-center, clinical study of AZD0120, a CD19/BCMA dual CAR T cell therapy, to evaluate the safety, tolerability, and efficacy in adult participants wit...

Boston, NY150 participantsAstraZeneca

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NCT03767426Recruiting

The Effect of Sleep Deprivation and Recovery Sleep on Emotional Memory and Affective Reactivity

To further understand the impact of acute sleep deprivation and recovery sleep on the processing of emotional information the investigators will address and attempt to answer three questions, (i) how ...

Boston, NY100 participantsBeth Israel Deaconess Medical Center

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NCT05393830Recruiting

The Effect of Sleep Loss on Emotion Regulation

The study is designed to investigate the impact of three nights of sleep restricted to 4 hours per night, on the processing and regulation of emotional information compared to Insomnia Disorder and co...

Boston, NY90 participantsBeth Israel Deaconess Medical Center

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NCT06925542Recruiting

A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease

This is a single-arm, open-label, multicenter, ascending dose Phase 1 study evaluating the safety and preliminary efficacy of CTX112 in adult subjects with refractory autoimmune diseases, including ac...

Boston, NY80 participantsCRISPR Therapeutics

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NCT06618040Recruiting

Bedtime Stories: Tailored Sleep Health Messaging for Caregivers

To date, there are very few established sleep health education models targeting caregivers of school-aged children from historically marginalized and/or low income communities. To address this signifi...

Boston, NY75 participantsBoston Children's Hospital

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NCT04652882Recruiting

Evaluating the Effects of Tasimelteon Vs. Placebo in Delayed Sleep-Wake Phase Disorder (DSWPD)

This is a multicenter, double-blind, randomized study to evaluate the efficacy and safety of a daily single oral dose of tasimelteon and matching placebo in male and female participants with DSWPD....

Boston, NY70 participantsVanda Pharmaceuticals

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NCT05293600Recruiting

Rescue Pharmacotherapy for OSA

Persistent obstructive sleep apnea (OSA) is common in people treated with mandibular advancement device (MAD) or hypoglossal nerve stimulation (HGNS). For most patients, these treatments are the last ...

Boston, NY70 participantsBrigham and Women's Hospital

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NCT07317336Recruiting

I-SLEPT: Integrated Sleep and Life Engagement Program for Transitions

Sleep is essential to functional recovery in rehabilitation settings; however, sleep is likely to be disrupted during rehabilitation admissions. Adverse effects of these disruptions do not subside aft...

Boston, NY60 participantsVA Office of Research and Development

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NCT07567560Recruiting

The Short Sleep Study

Natural Short Sleepers are defined as individuals who sleep fewer than 6 hours per night without any impact on health or daytime mental fatigue levels. Emerging evidence suggests that, in the general ...

Boston, NY34 participantsDanisco

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NCT07323524Recruiting

Dapagliflozin in Active Lupus Nephritis

Lupus nephritis is a chronic and life-threatening autoimmune cause of kidney disease that predominately impacts young people and can lead to kidney failure. Sodium-glucose co-transporter-2 inhibitors,...

Boston, NY33 participantsBrigham and Women's Hospital

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NCT06972303Recruiting

Mindfulness Meditation for Insomnia

The investigators will conduct a 3-arm, pilot RCT where participants (N=30) will be randomized in a 1:1:1 design to 4 weeks of instructed bedtime MM practice at night (n=10) vs. uninstructed MM (n=10)...

Boston, NY30 participantsBrigham and Women's Hospital

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NCT06121297Recruiting

RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus

RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus...

Boston, NY28 participantsCabaletta Bio

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NCT05350215Recruiting

Atomoxetine and DAW2022 on OSA Severity

Obstructive sleep apnea (OSA) is common and has major health implications but treatment options are limited. In previous research atomoxetine and oxybutynin showed promising effect at reducing OSA sev...

Boston, NY18 participantsBrigham and Women's Hospital

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NCT06286189Recruiting

Trazodone on OSA Endotypes

Obstructive sleep apnea (OSA) is common and has major health implications but treatment options are limited. Some OSA patients with low arousal threshold wake up prematurely during an obstructive even...

Boston, NY18 participantsBrigham and Women's Hospital

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NCT03858751Recruiting

Pharmacological Activation of HMN for OSA Aim 2

Obstructive sleep apnea (OSA) is common and has major health implications but treatment options are limited. OSA patients show a marked reduction in upper airway (UA) dilator muscle activity at sleep ...

Boston, NY16 participantsBrigham and Women's Hospital

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NCT07062770Recruiting

Assessment of Circuit Rebreathing During CPAP Therapy

The goal of this research is to better understand how different CPAP mask designs affect airflow and rebreathing of exhaled carbon dioxide (CO₂) during sleep in individuals with obstructive sleep apne...

Boston, NY13 participantsBrigham and Women's Hospital

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About Lupus Clinical Trials in Boston

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can affect the joints, skin, kidneys, brain, and other organs. It is more common in women and often involves periods of flares and remission. Treatment includes antimalarials, immunosuppressants, and biologics.

There are currently 22 lupus clinical trials recruiting participants in Boston, NY. These studies are seeking a combined 5,588 participants. Research is being sponsored by Lupus Research Alliance, National Heart, Lung, and Blood Institute (NHLBI), Juno Therapeutics, Inc., a Bristol-Myers Squibb Company and 11 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Lupus Clinical Trials in Boston — FAQ

Are there lupus clinical trials in Boston?

Yes, there are 22 lupus clinical trials currently recruiting in Boston, NY. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Boston?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you about next steps.

Are clinical trials in Boston free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Boston studies also compensate for your time and travel.

What lupus treatments are being tested?

The 22 active trials in Boston are testing new therapies including novel drugs, biologics, and treatment approaches for lupus.

Data updated July 13, 2026 from ClinicalTrials.gov