50 Ulcerative Colitis Clinical Trials in Boston, NY (2026)

Q: How do I join a clinical trial in Boston?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you.

Recruiting Ulcerative Colitis Studies in Boston

NCT01177618Recruiting

Boston Early-Onset Chronic Obstructive Pulmonary Disease (COPD) Study

Chronic obstructive pulmonary disease (COPD) is often caused by cigarette smoking, but genetic predisposition also influences COPD susceptibility. The purpose of this study is to identify genetic fact...

Boston, NY2,000 participantsBrigham and Women's Hospital

View Study Details

NCT07216521Recruiting

Intent of Surgery for IPMN

This multicenter retrospective observational cohort study seeks to: 1. Classify surgical intent in patients with resected Intraductal Papillary Mucinous Neoplasms (IPMN) and quantify the proportion o...

Boston, NY2,000 participantsNYU Langone Health

View Study Details

NCT06882356Recruiting

The Glaucoma and Retinopathy Screening Study

The goal of this clinical trial is to learn if a new screening approach including an artificial intelligence algorithm that analyzes fundus photographs, measurement of eye pressure and visual field te...

Boston, NY2,000 participantsMassachusetts Eye and Ear Infirmary

View Study Details

NCT06302439Recruiting

PROPEL - A Prospective Observational Patient Registry to Evaluate ENPP1 and ABCC6 Deficiency

The purpose of this prospective registry is to characterize the natural history of ectonucleotide pyrophosphatase/phosphodiesterase1(ENPP1) Deficiency and the infantile-onset form of adenosine triphos...

Boston, NY1,000 participantsInozyme Pharma

View Study Details

NCT01799915Recruiting

Natural History Study of Synucleinopathies

Synucleinopathies are a group of rare diseases associated with worsening neurological deficits and the abnormal accumulation of the protein α-synuclein in the nervous system. Onset is usually in late ...

Boston, NY800 participantsNYU Langone Health

View Study Details

NCT06586515Recruiting

MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors

The main purpose of this study is to assess safety \& tolerability and antitumor activity of LY3962673 as monotherapy and in combination with other chemotherapy agents in participants with KRAS G12D-m...

Boston, NY630 participantsEli Lilly and Company

View Study Details

NCT06089083Recruiting

PROmOting Gynecologic Cancer Patients With Frailty to Achieve Functional Recovery

This study seeks to understand how frailty, a term that describes people who are more vulnerable stressors such as a new medical problem, affects the outcomes and quality of life in adult patients wit...

Boston, NY500 participantsUniversity of California, San Francisco

View Study Details

NCT06621511Recruiting

OurSleepKit To Support CPAP Adherence

The goal of this clinical trial is to learn if a couple-focused mobile health intervention will improve the use of continuous positive airway pressure (CPAP), the primary treatment option for obstruct...

Boston, NY360 participantsNational Heart, Lung, and Blood Institute (NHLBI)

View Study Details

NCT07127978Recruiting

A Study Evaluating the Real-World Experience of Givinostat in Patients With Duchenne Muscular Dystrophy

This is a prospective observational study conducted to evaluate safety, tolerability, and functional outcomes of patients with DMD newly initiating oral givinostat or having started therapy within 6 m...

Boston, NY300 participantsITF Therapeutics LLC

View Study Details

NCT02989818Recruiting

Multi-center Evaluation of the Clinical Utility of ESD in the Western Population

The aim of this multi-center study is to prospectively document the clinical utility of ESD....

Boston, NY300 participantsUniversity of Florida

View Study Details

NCT06289491Recruiting

A Trial of Hydrus Microstent Versus Goniotomy

The goal of this clinical trial is to evaluate the comparative efficacy and safety of Hydrus Microstent, incisional goniotomy, and excisional goniotomy when combined with cataract surgery in patients ...

Boston, NY243 participantsMassachusetts Eye and Ear Infirmary

View Study Details

NCT05547165Recruiting

Percutaneous Intervention Versus Observational Trial of Arterial Ductus in Low Weight Infants

Patent Ductus Arteriosus is a developmental condition commonly observed among preterm infants. It is a condition where the opening between the two major blood vessels leading from the heart fail to cl...

Boston, NY240 participantsNationwide Children's Hospital

View Study Details

NCT05924477Recruiting

Glaucoma Drainage Device and Endothelial Cell Loss Compare Trial

Glaucoma Drainage Device and Endothelial Cell Loss Compare Trial (DECLARE) is a multi-center, outcome-masked, randomized clinical trial. The purpose of this study is to compare glaucoma drainage devic...

Boston, NY226 participantsUniversity of Pennsylvania

View Study Details

NCT07053423Recruiting

A Study to Investigate Airway Inflammation With Dupilumab Subcutaneously in Participants Aged ≥40 to ≤85 Years With Chronic Obstructive Pulmonary Disease.

LPS18583 is a multinational, randomized, double-blind, placebo-controlled, parallel-group, Phase 4 study with 2 treatment groups. The purpose of this study is to assess the effect of dupilumab compare...

Boston, NY218 participantsSanofi

View Study Details

NCT07209436Recruiting

Impact of Pectoral Versus Paravertebral Blocks on Pain and Physical Well-Being in Implant-Based Breast Reconstruction

The broad aim of this study is to compare the effectiveness of paravertebral and pectoral blocks on pain and physical well-being of patients undergoing immediate implant-based breast reconstruction....

Boston, NY212 participantsAmy Colwell

View Study Details

NCT07217717Recruiting

Using 18F-FAPI PET to Detect Metastatic Disease in Patients That Have Pancreatic Ductal Adenocarcinoma (PDAC)

This is a multi-site, open-label, non-randomized, single dose study to assess the clinical utility of \[¹⁸F\]FAPI-74 PET/CT in the detection of metastatic disease in individuals with pathologically co...

Boston, NY200 participantsSOFIE

View Study Details

NCT05736848Recruiting

A Retrospective Assessment of OviTex PRS (OviTex)

The objective of this retrospective-prospective, observational study is to evaluate the safety profile overall and within two device types of OviTex PRS in previous pre-pectoral or sub-pectoral implan...

Boston, NY200 participantsTela Bio Inc

View Study Details

NCT07237516Recruiting

Zymfentra (Infliximab-dyyb) REal World Cohort STudy

The goal of this observational study is to learn about how effective Zymfentra (IFX=dyyb) is when treating patients with Crohn's disease (CD) and ulcerative colitis (UC) Does Zymfentra lead to a reduc...

Boston, NY200 participantsUniversity of North Carolina, Chapel Hill

View Study Details

NCT07023614Recruiting

A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy

FORTITUDE-HCM is a global, multicenter, double-blind, parallel-group, placebo-controlled Phase 2b study that will assess the efficacy and safety of ninerafaxstat compared to placebo on top of Standard...

Boston, NY165 participantsImbria Pharmaceuticals, Inc.

View Study Details

NCT06352645Recruiting

Evaluation of Safety and Efficacy of Bixdo Ultra Compact Water Flosser

The objective of the present randomized controlled trial is to evaluate the safety and efficacy of the use of Bixdo A30 Pro Ultra Compact Water Flosser (also referred to as the "Bixdo A30 Portable Wat...

Boston, NY165 participantsTufts University

View Study Details

NCT06562192Recruiting

Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers

The purpose of this study is to evaluate the safety, tolerability, dosimetry and preliminary efficacy of \[177Lu\]Lu-NNS309 and the safety and imaging properties of \[68Ga\]Ga-NNS309 in patients aged ...

Boston, NY162 participantsNovartis Pharmaceuticals

View Study Details

NCT07131592Recruiting

Effect of Intravenous and Topical Tranexamic Acid on Drain Output in Breast Reduction Surgery

This study aims to evaluate whether tranexamic acid (TXA), a medication that helps reduce bleeding, can decrease fluid drainage after breast reduction surgery. Participants will be randomly assigned t...

Boston, NY160 participantsMassachusetts General Hospital

View Study Details

NCT07168499Recruiting

Diet and Stress Management Combined With Advanced Therapy for Crohn's and Ulcerative Colitis

Inflammatory Bowel Disease (IBD), which includes Crohn's Disease (CD) and Ulcerative Colitis (UC), is a chronic, immune-mediated disease characterized by recurrent episodes of relapse. The goal of thi...

Boston, NY160 participantsMassachusetts General Hospital

View Study Details

NCT04844606Recruiting

A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)

The main purpose of this study is to evaluate the long-term efficacy of mirikizumab in pediatric participants with ulcerative colitis (UC) or Crohn's disease (CD). The study will last about 172 weeks ...

Boston, NY150 participantsEli Lilly and Company

View Study Details

NCT05934565Recruiting

Mindful Steps 2.0: Promoting Physical Activity in Patients With COPD and HF

The goal of this fully-remote randomized controlled trial is to test the efficacy of Mindful Steps in facilitating physical activity compared to usual standard of care among 136 patients with COPD and...

Boston, NY136 participantsBeth Israel Deaconess Medical Center

View Study Details

NCT05987852Recruiting

Hyperbaric Oxygen Therapy for Ulcerative Colitis (HBOT-UC)

Chronic intestinal hypoxia and accompanying mucosal inflammation is a hallmark of ulcerative colitis (UC). Hyperbaric oxygen therapy (HBOT) involves breathing 100% oxygen under increased atmospheric p...

Boston, NY126 participantsNorthwestern University

View Study Details

NCT06551129Recruiting

Real-world Patient Reported Outcomes Among Patients Treated With Camzyos

This real-world study will assess changes in health status among participants with symptomatic obstructive hypertrophic cardiomyopathy who are treated with mavacamten in the real world....

Boston, NY118 participantsBristol-Myers Squibb

View Study Details

NCT05016908Recruiting

Extracellular RNA Biomarkers of Duchenne Muscular Dystrophy

Current methods of measuring the response to new treatments for muscular dystrophies involve the examination of small pieces of muscle tissue called biopsies. The investigators are interested in findi...

Boston, NY100 participantsMassachusetts General Hospital

View Study Details

NCT04508088Recruiting

Skeletal Health and Bone Marrow Composition in Newly Diagnosed Adolescents With Crohn Disease

The investigators will be evaluating bone marrow composition via magnetic resonance imaging in newly diagnosed adolescents with Crohn disease (CD) compared to healthy, matched controls. The investigat...

Boston, NY92 participantsMassachusetts General Hospital

View Study Details

NCT05332639Recruiting

Personalized Risk Estimation for Crohn's Disease (PRE-Crohn's): Implementation and Feasibility

The aim of this study is to develop and assess the feasibility and effect of a web-based, personalized risk-estimation for Crohn's disease (PRE-Crohn's) tool on behaviors and biomarkers associated wit...

Boston, NY80 participantsMassachusetts General Hospital

View Study Details

NCT06841705Recruiting

Early Vedolizumab as First-Line for Immune-Related Colitis Therapy Trial

The goal of this clinical trial is to compare the effectiveness and safety of Vedolizumab with a short course of steroids compared to standard course of steroids for the treatment of immune checkpoint...

Boston, NY80 participantsShilpa Grover, MD, MPH

View Study Details

NCT05293600Recruiting

Rescue Pharmacotherapy for OSA

Persistent obstructive sleep apnea (OSA) is common in people treated with mandibular advancement device (MAD) or hypoglossal nerve stimulation (HGNS). For most patients, these treatments are the last ...

Boston, NY70 participantsBrigham and Women's Hospital

View Study Details

NCT03758521Recruiting

Natural History Study of Patients With Succinic Semialdehyde Dehydrogenase (SSADH) Deficiency

Succinic Semialdehyde Dehydrogenase deficiency (SSADHD) is a rare autosomal recessive disease that interferes with the catabolism of the major inhibitory neurotransmitter gamma-amino butyric acid (GAB...

Boston, NY55 participantsBoston Children's Hospital

View Study Details

NCT06655415Recruiting

Family Members At INcreased-risk for Developing Inflammatory Bowel Disease

First-degree relatives of people with inflammatory bowel disease ("IBD," including Crohn's disease and ulcerative colitis) have an increased risk for developing IBD themselves. This study will follow ...

Boston, NY50 participantsMassachusetts General Hospital

View Study Details

NCT07047807Recruiting

PDAC-PATHWAYS: A Digital Informational and Supportive Care App for Patients Initiating Neoadjuvant Therapy for Pancreatic Ductal Adenocarcinoma

This study aims to refine and pilot test PDAC-PATHWAYS, a digital informational and supportive care app for patients who are initiating neoadjuvant therapy for pancreatic ductal adenocarcinoma (PDAC)....

Boston, NY50 participantsMassachusetts General Hospital

View Study Details

NCT07064798Recruiting

Cryocompression for CIPN

This study aims to evaluate the effectiveness, tolerability, and safety of using cooling therapy and pressure (cryocompression) to reduce peripheral neuropathy, a condition affecting the nerves supply...

Boston, NY50 participantsDana-Farber Cancer Institute

View Study Details

NCT04331639Recruiting

High Dose Interval Vitamin D Supplementation in Patients With Inflammatory Bowel Disease Receiving Biologic Therapy

The investigators will be administering oral high dose interval vitamin D, concurrently when participants are receiving biologic therapy for their inflammatory bowel disease. The investigators will be...

Boston, NY50 participantsBoston Children's Hospital

View Study Details

NCT04440280Recruiting

Targeting Reactive Oxygen Species Production as a Novel Therapeutic in Fuch's Endothelial Corneal Dystrophy

This protocol will investigate whether topical application of N-acetyl cysteine (NAC) eye drops decreases oxidative stress and confers cytoprotection in patients with FECD....

Boston, NY45 participantsMassachusetts Eye and Ear Infirmary

View Study Details

NCT07224490Recruiting

Kisspeptin to Quantify GnRH Neuronal Function in Health and Disease

The objective of this protocol is to use a case-control paradigm to compare the response to an intravenous administration of kisspeptin in individuals with and without post-covid-19 syndrome. The stud...

Boston, NY40 participantsStephanie B. Seminara, MD

View Study Details

NCT05287126Recruiting

A Study to Evaluate Etrasimod Treatment in Adolescents With Ulcerative Colitis

The purpose of this study is to determine the safety, efficacy, and pharmacokinetics (PK) of etrasimod for the treatment of moderately to severely active ulcerative colitis in adolescents (≥ 12 years ...

Boston, NY36 participantsPfizer

View Study Details

NCT05655949Recruiting

Y-90 With Durvalumab/Gem/Cis in Intrahepatic Cholangio

This trial is designed to study a combination of interventions (chemotherapy, immunotherapy, and radiation) as a potential new treatment for bile duct cancer that cannot be removed with surgery. The ...

Boston, NY30 participantsBeth Israel Deaconess Medical Center

View Study Details

NCT07024615Recruiting

A Study of ASP2138 Given Before Surgery, Then Chemotherapy After Surgery, in People With Pancreatic Ductal Cancer

Some people with pancreatic ductal cancer (PDAC) have a protein called Claudin 18.2 (CLDN18.2) in their tumor. ASP2138 is thought to work by binding to CLDN18.2 and a protein on a type of immune cell ...

Boston, NY25 participantsAstellas Pharma Global Development, Inc.

View Study Details

NCT06807294Recruiting

Feasibility Testing of a Tai Chi Program for Chemotherapy-Induced Peripheral Neuropathy Treatment (TCT)

This research is being done to determine whether a 12-week virtual Tai Chi training program, designed to improve balance and small nerve fiber function, is feasible and acceptable among cancer survivo...

Boston, NY21 participantsDana-Farber Cancer Institute

View Study Details

NCT05642455Recruiting

SPEARHEAD-3 Pediatric Study

This is a pediatric basket study to investigate the safety and efficacy of afamitresgene autoleucel in HLA-A\*02 eligible and MAGE-A4 positive subjects aged 2-17 years of age with advanced cancers....

Boston, NY20 participantsAdaptimmune

View Study Details

NCT07290244Recruiting

Evaluating ER-100 for Safety in People With Glaucoma or Non-Arteritic Anterior Ischemic Optic Neuropathy (Optic Nerve Conditions)

The goal of this clinical trial is to evaluate the safety and tolerability of a single dose of ER-100 in adults with optic nerve conditions, specifically Open Angle Glaucoma (OAG) and Non-Arteritic An...

Boston, NY18 participantsLife Biosciences Inc.

View Study Details

NCT06286189Recruiting

Trazodone on OSA Endotypes

Obstructive sleep apnea (OSA) is common and has major health implications but treatment options are limited. Some OSA patients with low arousal threshold wake up prematurely during an obstructive even...

Boston, NY18 participantsBrigham and Women's Hospital

View Study Details

NCT05350215Recruiting

Atomoxetine and DAW2022 on OSA Severity

Obstructive sleep apnea (OSA) is common and has major health implications but treatment options are limited. In previous research atomoxetine and oxybutynin showed promising effect at reducing OSA sev...

Boston, NY18 participantsBrigham and Women's Hospital

View Study Details

NCT03858751Recruiting

Pharmacological Activation of HMN for OSA Aim 2

Obstructive sleep apnea (OSA) is common and has major health implications but treatment options are limited. OSA patients show a marked reduction in upper airway (UA) dilator muscle activity at sleep ...

Boston, NY16 participantsBrigham and Women's Hospital

View Study Details

NCT05734196Recruiting

The ENERGY Study: Evaluation of Safety and Tolerability of INZ-701 in Infants With ENPP1 Deficiency or ABCC6 Deficiency

The primary purpose of Study INZ701-104 (the ENERGY study) is to assess the safety and tolerability of INZ-701 in infants with ENPP1 Deficiency or with ABCC6 Deficiency....

Boston, NY16 participantsInozyme Pharma

View Study Details

NCT07062770Recruiting

Assessment of Circuit Rebreathing During CPAP Therapy

The goal of this research is to better understand how different CPAP mask designs affect airflow and rebreathing of exhaled carbon dioxide (CO₂) during sleep in individuals with obstructive sleep apne...

Boston, NY13 participantsBrigham and Women's Hospital

View Study Details

About Ulcerative Colitis Clinical Trials in Boston

Ulcerative colitis is a chronic inflammatory bowel disease that causes inflammation and ulcers in the innermost lining of the colon and rectum. It typically presents with bloody diarrhea, abdominal pain, and urgency. Treatment includes aminosalicylates, corticosteroids, immunosuppressants, and biologics.

There are currently 50 ulcerative colitis clinical trials recruiting participants in Boston, NY. These studies are seeking a combined 13,964 participants. Research is being sponsored by Brigham and Women's Hospital, NYU Langone Health, Massachusetts Eye and Ear Infirmary and 28 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Ulcerative Colitis Clinical Trials in Boston — FAQ

Are there ulcerative colitis clinical trials in Boston?

Yes, there are 50 ulcerative colitis clinical trials currently recruiting in Boston, NY. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Boston?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you about next steps.

Are clinical trials in Boston free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Boston studies also compensate for your time and travel.

What ulcerative colitis treatments are being tested?

The 50 active trials in Boston are testing new therapies including novel drugs, biologics, and treatment approaches for ulcerative colitis.

Data updated July 13, 2026 from ClinicalTrials.gov