6 B-Cell Acute Lymphoblastic Leukemia Clinical Trials in Philadelphia, PA (2026)

Q: How do I join a clinical trial in Philadelphia?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Philadelphia research site will contact you.

Recruiting B-Cell Acute Lymphoblastic Leukemia Studies in Philadelphia

NCT04276870Recruiting

Orphan Indications for CD19 Redirected Autologous T Cells

This is an open-label, four-cohort, phase 2 study to determine the efficacy of CART19 in pediatric and young adult patientswith hypodiploid (Cohort A) or t(17;19) B-ALL (Cohort B), infants with very h...

Philadelphia, PAPHASE2133 participantsStephan Grupp MD PhD

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NCT07223021Recruiting

A Study of Fludarabine Dosing in Children and Young Adults With B-cell Acute Lymphoblastic Leukemia

The researchers are doing this study to find out whether PK-targeted fludarabine is an effective Lymphodepletion (LD) chemotherapy approach for people with relapsed/refractory B-cell acute lymphoblast...

Philadelphia, PAPHASE3130 participantsMemorial Sloan Kettering Cancer Center

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NCT05480449Recruiting

Autologous HuCART19 T Cells Manufactured Using the CliniMACS Prodigy Platform for Pediatric B-ALL (huCART19 Prodigy)

This study will determine the safety and efficacy of moving to a second-generation manufacturing process using the CliniMACS Prodigy platform to manufacture huCART19 cells for patients with B cell Acu...

Philadelphia, PAPHASE1115 participantsStephan Grupp MD PhD

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NCT06579469Recruiting

Prospective Evaluation Of Delayed Effects Of Pediatric Car T Cell Therapy

This study is being done to learn more about the short-term and long-term side effects of CAR-T cell therapy. Specifically, researchers want to know how often patients get infections, have delays in r...

Philadelphia, PA100 participantsSt. Jude Children's Research Hospital

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NCT05674175Recruiting

Co-administration of CART22-65s and huCART19 for B-ALL

This study will evaluate the safety and efficacy of administering two CAR T cell products, huCART19 and CART22-65s, in children with advanced B cell Acute Lymphoblastic Leukemia (B-ALL)....

Philadelphia, PAPHASE193 participantsStephan Grupp MD PhD

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NCT04150497Recruiting

Phase 1/2 Study of UCART22 in Patients With Relapsed or Refractory CD22+ B-cell Acute Lymphoblastic Leukemia (BALLI-01)

This is a first-in-human, open-label, dose escalation and expansion study of UCART22 administered intravenously to patients with relapsed or refractory B-cell acute Lymphoblastic Leukemia (B-ALL). The...

Philadelphia, PAPHASE152 participantsCellectis S.A.

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About B-Cell Acute Lymphoblastic Leukemia Clinical Trials in Philadelphia

B-cell acute lymphoblastic leukemia (B-ALL) is a fast-growing cancer of the B-type lymphocyte white blood cells. It is the most common childhood cancer but can also occur in adults. Treatment includes chemotherapy, targeted therapy, and CAR-T cell therapy.

There are currently 6 b-cell acute lymphoblastic leukemia clinical trials recruiting participants in Philadelphia, PA. These studies are seeking a combined 623 participants. Research is being sponsored by Stephan Grupp MD PhD, Memorial Sloan Kettering Cancer Center, St. Jude Children's Research Hospital and 1 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

B-Cell Acute Lymphoblastic Leukemia Clinical Trials in Philadelphia — FAQ

Are there b-cell acute lymphoblastic leukemia clinical trials in Philadelphia?

Yes, there are 6 b-cell acute lymphoblastic leukemia clinical trials currently recruiting in Philadelphia, PA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Philadelphia?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Philadelphia research site will contact you about next steps.

Are clinical trials in Philadelphia free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Philadelphia studies also compensate for your time and travel.

What b-cell acute lymphoblastic leukemia treatments are being tested?

The 6 active trials in Philadelphia are testing new therapies including novel drugs, biologics, and treatment approaches for b-cell acute lymphoblastic leukemia.

Data updated October 16, 2026 from ClinicalTrials.gov