Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Acromegaly Clinical Trials
Acromegaly clinical trials are recruiting across 16 cities. Here are the cities with the most active studies:
Acromegaly Trial Phases
4 research organizations are sponsoring acromegaly trials.
About Acromegaly
Acromegaly is a hormonal disorder caused by excess growth hormone, usually from a pituitary gland tumor. It results in enlargement of hands, feet, and facial features. Treatment includes surgery to remove the tumor, medications to reduce growth hormone, and radiation therapy.
Clinical trials are advancing new treatments for acromegaly. Currently, 5 studies are recruiting a combined 339 participants across the United States. Research is being conducted by 4 organizations including Debiopharm International SA, Mayo Clinic, Alexion Pharmaceuticals, Inc. and 1 others.
2026 Acromegaly Research Landscape
As of July 2026, the acromegaly clinical trial landscape includes 5 actively recruiting studies across 16 cities in the United States. These studies are collectively seeking 339 participants, with an average enrollment target of 68 per study.
The research spans multiple phases of development: 2 studies are in PHASE1, 1 study is in PHASE3, 1 study is in PHASE2. The presence of Phase 3 trials indicates that some acromegaly treatments are in late-stage testing and may be approaching regulatory review.
Research is being led by 4 different organizations, including Debiopharm International SA, Mayo Clinic, Alexion Pharmaceuticals, Inc., Marea Therapeutics.
Geographically, acromegaly trials are most concentrated in Los Angeles, California (2 trials); Boston, Massachusetts (2 trials); Las Vegas, Nevada (2 trials); New York, New York (2 trials); Portland, Oregon (2 trials) and 7 other cities.
Featured Acromegaly Studies
Highlighted recruiting studies for acromegaly, selected by enrollment size and research scope.
A Study to Assess the Efficacy and Safety of Debio 4126 in Participants With Acromegaly Previously Treated With Somatostatin Analogs
The primary purpose of this study is to assess the effect of Debio 4126 in the maintenance of the levels of insulin-like growth factor 1 (IGF-1) ≤1x upper limit of normal (ULN) in the double-blind period (Period 1) in comparison to placebo at week 36.
Evaluation of Intraoperative Contrast Enhanced Ultrasound for the Identification of Pituitary Adenoma in Cushing's Disease Compared to Other Pituitary Tumors
This pilot and feasibility study aims to combine recent advances in ultrasound imaging, specifically an endonasal transducer array and contrast enhanced ultrasound, to offer an intraoperative image-guided solution for lesion-specific surgical resection to impact clinical outcome. Should this imaging approach help isolate specific lesions and prevent surgical resection of normal pituitary tissue in...
ALXN2420 Versus Placebo in Combination With Somatostatin Analogs in Participants With Acromegaly
The primary objective of this study is to evaluate the efficacy of 15-week treatment with ALXN2420 versus placebo for decreasing insulin-like growth factor IGF-1 levels, when administered in combination with somatostatin analog (SSA) therapy to adult participants with acromegaly.
Frequently Asked Questions About Acromegaly Clinical Trials
Are there acromegaly clinical trials near me?
Yes, there are 5 acromegaly clinical trials currently recruiting across 16+ cities in the United States, including Los Angeles, California; Boston, Massachusetts; Las Vegas, Nevada. Browse the studies above to find one at a location convenient for you.
How do I join a acromegaly clinical trial?
To join a acromegaly clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are acromegaly clinical trials free?
Yes, participation in acromegaly clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of acromegaly treatments are being studied?
Current acromegaly clinical trials are testing a range of approaches across PHASE1 (2 studies), PHASE3 (1 study), PHASE2 (1 study). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 4 research organizations.
Is it safe to participate in acromegaly clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 14, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 14, 2026 · Data from ClinicalTrials.gov